孕期低钙饲养对胎鼠和幼鼠下颌骨发育的影响  

The effect of low calcium intake during pregnancy in rats on development of mandibular bone fetuses and infants

作　　者：高翠林[1] 李善 刘汕宗[1] 薄爱华[2] 邢立强[2] 许永利[2] 

机构地区：[1]张家口医学院第一附属医院口腔科,075029 [2]张家口医学院电镜室

出　　处：《现代口腔医学杂志》2001年第2期84-85,I002,共3页Journal of Modern Stomatology

摘　　要：目的　探讨大鼠孕期低钙饲养对仔鼠下颌骨发育的影响。方法　实验组大鼠孕期低钙饲养 (0 .0 3%Ca2 + ) ,用光电镜观察刚出生仔鼠和断乳期幼鼠下颌骨发育状况。结果　实验组下颌骨生长发育迟缓 ,软骨细胞和骨细胞超微结构异常。结论　孕鼠低钙饲养能导致幼鼠下颌生长发育迟缓。Objective To investigate the effects of mandibulae development in fetuses and infants,during pregnancy of rat with low calcium intake.Methods 8 pregnants rats were control group.16 pregnants ras were experimental group,Which received 0.03% calcium diet.The development of mandible of newborn and at end of lactation rats,was observed with light and electron microscopy.Results The development of mandble was slow on a low calcium diet at birth and end of lactation rat of expermental group,the ultrastructure of chondracytes and bone cells were abnormal.Conclusion The growth and development of the mandibular bone of the fetuses were retarded.

关 键 词：大鼠 低钙 超微结构 下颌骨发育 孕期 

分 类 号：R715.3[医药卫生—妇产科学]