3.0T MR 扩散加权成像在脊髓型颈椎病中的应用  

The application of diffusion weighted imaging in the cervical spondylotic myelopathy with 3.0T MRI

作　　者：曹开明[1] 郝楠馨[1] 王轶彬[1] 宗根林[1] 杜育杉[1] 

机构地区：[1]同济大学附属上海市东方医院放射科,上海200120

出　　处：《实用放射学杂志》2014年第6期918-922,共5页Journal of Practical Radiology

基　　金：浦东新区卫生局卫生科技项目（PW2010A-1）.

摘　　要：目的：探讨3.0T MR 扩散加权成像（DWI）作为定量分析方法在慢性脊髓型颈椎病诊断中的临床价值。方法38例慢性脊髓型颈椎病（CSM）患者与20例志愿者（对照组）行常规颈椎矢状位 T2 WI、横断位 DWI 扫描，并重建矢状位表观扩散系数（ADC）图像；计算各组脊髓 T2 WI 高信号例数并测量脊髓 ADC 值；CSM 组分别测量脊髓 C3水平、受压或信号异常部位以及 T1-T2水平 ADC 值，对照组测量 C3、C4-C6、T1-T2水平脊髓 ADC 值。结果 CSM 组Ⅰ-Ⅳ级分别有3例、1例、6例、8例出现脊髓高信号，对照组2例出现脊髓 T2 WI 高信号；脊髓受压部位 ADC 值随 CSM 分级增高而逐渐增高，对照组、CSM 组Ⅰ-Ⅱ级与 CSM Ⅳ级之间 ADC 均值差别有统计学意义。结论 CSM 患者脊髓 ADC 值改变要早于脊髓信号的改变；ADC 值可以反映 CSM 患者脊髓的受压程度。Objective To explore the value of diffusion weighted imaging （DWI）as a quantitative analysis tool for chronic cervical spondylotic myelopathy （CSM）with 3.0T MRI.Methods Cervical routine MR T2-weighted imaging（T2 WI）and diffusion weighted imaging were performed in 38 patients with cervical spondylotic myelopathy （CSM group）and 20 healthy volunteers （control group）,and sagittal image of apparent diffusion coefficient （ADC）was reconstructed.The number of high T2 signal of the spinal cord were calculated in both healthy volunteers and CSM patients.The ADC values of CSM groups were measured in C3,T1 -C2 level and the compression or abnormal signal parts of the spinal cord;the control group measured C3、C4-C6 and T1 -T2 level in the spinal cord.Results There were 3 cases,1 case,6 cases and 8 cases high T2 signals in CSM patients from Ⅰ to Ⅳ levels,while there were 2 cases show high T2 signals in control group,respectively.The mean ADC values of the compression part were gradual-ly increased in CSM group from Ⅰ to Ⅳ level.There were significant differences of the mean ADC values of compression part be-tween the control group,CSMⅠ-Ⅱ level and the CSM Ⅳ level.Conclusion From our study,the change of ADC value of spine cord occured earlier than the change of signal in CSM patients.Therefore,the ADC value of spine cord might reflect the degree of spinal cord compression from CSM patients.

关 键 词：颈椎病 磁共振扩散加权成像 表观扩散系数 

分 类 号：R681.5[医药卫生—骨科学] R445.2[医药卫生—外科学]