前列腺素E_1在慢性肺源性心脏病心力衰竭治疗中的疗效观察  

Observation on the Effect of Prostaglandin E_1 Treatment in Pulmonary Heart Disease with Heart Failure

作　　者：贺淑媛[1] 李江林[1] 杨超[1] 

机构地区：[1]深圳市人民医院药剂科,广东深圳518020

出　　处：《黑龙江医学》2014年第6期636-637,共2页Heilongjiang Medical Journal

摘　　要：目的观察前列腺素El在治疗慢性肺源性心脏病心力衰竭中的临床效果。方法将60例慢性肺源性心脏病心力衰竭病例随机分为对照组(n=30)和观察组(n=30)。对照组采用常规治疗方法,观察组在常规治疗方法的基础上加用前列腺素El脂微球。结果使用前列腺素E1脂微球一个疗程后,动脉血动脉氧分压明显上升,而二氧化碳分压显著下降,同时肺动脉收缩压明显降低,心脏指数明显增加。结论前列腺素E1有助于改善慢性肺源性心脏病心力衰竭。Objective To observe the clinical effect of prostaglandin Eltreatment in pulmonary heart disease with heart failure.Methods 60 cases were randomly divided into control group（ 30 cases） with routine therapy and experimental group（ 30 cases） with prostaglandin E1 based on routine treatment. Results After one period of treatment,the value of PaO2 in experimental group was increased significantly,whereas PaCO2 value decreased significantly. The pulmonary artery systolic pressure（ PASP） in experimental group significantly decreased and cardiac index（ CI） significantly increased compared with control group. Conclusion Prostaglandin E1 was obviously beneficial to the treatment of pulmonary heart disease with heart failure.

关 键 词：前列腺素E1 肺源性心脏病 心力衰竭 

分 类 号：R541.5[医药卫生—心血管疾病]