小剂量氯胺酮对儿童七氟醚麻醉后苏醒期躁动作用的临床研究  

Clinical Study of Low Dose Ketamine on Children Agitation After Sevoflurane Anesthesia Recovery

作　　者：陈志峰[1] 丁勇[1] 王雪玲[1] 蔡杰衡[1] 

机构地区：[1]广东药学院附属第一医院,广东广州510080

出　　处：《黑龙江医学》2014年第6期673-674,共2页Heilongjiang Medical Journal

摘　　要：目的使用不同剂量氯胺酮应用于儿童七氟醚麻醉后苏醒期,探讨其对小儿麻醉后疼痛和躁动的应用价值。方法以七氟醚全麻下行浅表手术的儿童为研究对象,随机将分为实验组、观察组和对照组,麻醉后分别静注0.50 mg/kg、0.25 mg/kg的氯胺酮静脉推射和生理盐水,对患儿苏醒后疼痛评分及躁动情况等情况进行记录和统计分析。结果实验组、观察组和对照组3组患儿术后疼痛评分结果呈现显著差异性(P<0.05),3组患儿苏醒时间、并发症发生以及拔管时间等差异无统计学意义(P>0.05)。结论氯胺酮的小剂量使用有助于减少小儿七氟醚麻醉后苏醒期的躁动症状,临床观察显示0.50 mg/kg的剂量能达到较好的效果。Objective Through using different doses of Ketamine in children sevoflurane anesthesia recovery period,to explore the value of pain and agitation in children. Methods Sevoflurane anesthesia superficial surgery for children for the study were randomly divided into the experimental group,the observation group and control group,respectively,with intravenous anesthesia 0. 50mg /kg,0. 25mg /kg of Ketamine and saline on the circumstances after anesthesia,such as pain scores and agitation in children after waking recorded and statistical analysis. Results The experimental group and control group was observed,children of three groups with postoperative pain score results showed a significant difference（ P〈0. 05）,and children of three groups with recovery time,complications and estuation time difference was not statistically significant（ P〉0. 05）. Conclusion The use of small doses of Ketamine can help reduce children after sevoflurane anesthesia symptoms of agitation. Clinical observation indicates that the dose of 0. 50mg /kg can achieve better results.

关 键 词：氯胺酮 小儿 七氟醚 麻醉 苏醒期躁动 疼痛评分 

分 类 号：R614[医药卫生—麻醉学]