左氧氟沙星联合利福喷丁治疗复治肺结核病疗效观察  

Observation of the Tuberculosis Retreatment Effect of Ofloxacin Combined with Rifapentine

作　　者：王美华[1] 郑定容[1] 

机构地区：[1]深圳市宝安区西乡人民医院,广东深圳518102

出　　处：《黑龙江医学》2014年第6期720-721,共2页Heilongjiang Medical Journal

摘　　要：目的观察左氧氟沙星联合利福喷丁在复治肺结核病治疗中的疗效。方法采用随机配对分组将172例复治肺结核病患者分为治疗组、对照组,每组各86例。治疗组给予左氧氟沙星联合利福喷丁治疗,对照组用左氧氟沙星联合利福平治疗。结果治疗8个月后,两组的治疗效果进行比较。治疗组痰菌阴转率、疗程结束时痰菌培养阳性率、病灶总吸收率和空洞闭合率均明显优于对照组。结论含左氧氟沙星联合利福喷丁方案在复治肺结核病治疗中,更有助于痰菌阴转、病灶吸收和空洞闭合。Objective To observe the tuberculosis retreatment effect of the treatment group treated with ofloxacin combined with rifapentine. Methods 172 cases were randomly divided into treatment group and control group,with 86 cases in each group. The treatment group were treated with ofloxacin combined with rifapentine,and the control group were treated with ofloxacin combined with rifampicin. Results The curative effect of two groups were compared after eight months. In the treatment group,phlegm germ feminine negative conversion rate,culture positive rate of sputum,lesions total absorptivity and cavity closure rate were significantly better than the control group.Conclusion The retreatment tuberculosis treated with ofloxacin combined rifapentine can help phlegm germ feminine negative conversion rate,lesions absorption and empty close.

关 键 词：复治肺结核病 左氧氟沙星 利福喷丁 利福平 疗效 

分 类 号：R521[医药卫生—内科学]