温润宣通法治疗慢性阻塞性肺疾病稳定期与支气管哮喘慢性持续期的疗效影响因素分析  

Impact factors of Wenrun Xuantong method in treating stable chronic obstructive pulmonary diseases and bronchial asthma in chronic persistent period

作　　者：阎玥[1] 杨璐[2] 王辛秋[1] 史琦[1] 宋芊[2] 李文成[2] 李友林[1] 

机构地区：[1]中日友好医院,北京100029 [2]北京中医药大学,北京100029

出　　处：《中华中医药杂志》2014年第6期1954-1956,共3页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：中医药行业科研专项项目(No.7-21)~~

摘　　要：目的:探索年龄和季节对同一方药治疗慢性阻塞性肺疾病稳定期(S-COPD)与支气管哮喘慢性持续期患者疗效的影响。方法:采用多中心、分段随机分组、平行对照(1∶1)、双盲的临床试验研究设计,将272例S-COPD和支气管哮喘慢性持续期患者随机分为试验组和对照组,疗程6周,治疗前后进行患者主症和体征有效率评价。结果:依据年龄分组,治疗后S-COPD和支气管哮喘慢性持续期试验组患者主症+体征有效率之间差异无统计学意义;依据季节分组,治疗后S-COPD和支气管哮喘慢性持续期试验组患者主症+体征有效率之间差异有统计学意义(P<0.05)。结论:年龄对温润宣通法治疗S-COPD和支气管哮喘慢性持续期患者的疗效影响不明显,而季节对温润宣通法治疗S-COPD和支气管哮喘慢性持续期患者的疗效影响明显,夏秋季优于冬春季。Objective： To explore the effects of age and season on patients with stable chronic obstructive pulmonary diseases （S-COPD） and bronchial asthma in chronic persistent period with the same treatment. Methods： Clinical trial research design of multi-central, stratified randomization, parallel control （1：1） and double blind was adopted to randomly divide 272 patients with S-COPD and bronchial asthma in chronic persistent period into western medicine conventional treatment combined with relieving asthma prescription group and western medicine conventional treatment combined with traditional Chinese medicine placebo group. The course of the treatment was 6 weeks, and the effective rate of main symptoms and signs was evaluated before and after the treatment. Results： Grouping according to age, the difference of the effective rate of main symptoms plus signs between patients with S-COPD and bronchial asthma in chronic persistent period in western medicine conventional treatment combined with relieving asthma prescription group after the treatment was not statistically significant （P〉0.05）; grouping according to season, the difference of the effective rate of main symptoms plus signs between patients with S-COPD and bronchial asthma in chronic persistent period in western medicine conventional treatment combined with relieving asthma prescription group after the treatment was statistically significant （P〈0.05）. Conclusion： The effect of age to patients with S-COPD and bronchial asthma in chronic persistent period with the treatment of Wenrnn Xuantong method was not obvious, and the effect of season to patients of S-COPD and bronchial asthma in chronic persistent period with the treatment of Wenrnn Xuantong method was obvious, summer and autumn were superior to winter and spring.

关 键 词：慢性阻塞性肺疾病 支气管哮喘 年龄 季节 温润宣通 

分 类 号：R259[医药卫生—中西医结合]