艾灸对急性胃溃疡大鼠胃黏膜组织形态学和血流量的影响  

Influence on the morphology and blood flow volume of the gastric mucosa in rats with acute gastric ulcer treated by moxibustion

作　　者：龚安[1,2] 杨宗保[1] 施彬彬[1] 刘琼[2] 谢宇锋 

机构地区：[1]厦门大学医学院,厦门361005 [2]江西中医药大学,南昌330004 [3]深圳市福田区中医院,深圳518000

出　　处：《中华中医药杂志》2014年第6期2001-2003,共3页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家自然科学基金项目(No.30960484;No.81260556)~~

摘　　要：目的:研究艾灸对急性胃溃疡大鼠胃黏膜组织形态的变化和血流量的影响,探讨艾灸促进胃黏膜损伤修复的生物学机制。方法:将大鼠随机分为正常组、模型组、胃经穴组和对照点组,采用束缚冷应激法制作急性胃溃疡大鼠模型,光镜下观察大鼠胃黏膜溃疡指数,多导生理记录仪检测大鼠胃黏膜血流量。结果:与模型组比较,胃经穴组大鼠的胃黏膜溃疡指数值均降低,胃黏膜形态学明显改善,胃黏膜血流量显著增加(P<0.01);与对照点组比较,胃经穴组大鼠胃黏膜溃疡指数、形态学和血流量改善更为明显(P<0.01)。结论:艾灸可增加胃黏膜血流量,促进胃黏膜的损伤修复,并且存在一定的经脉脏腑相关性。Objective： To study the biological repair mechanisms of gastric mucosa damage, through the effect of morphology and blood flow volume of gastric mucosa in rats with acute gastric ulcer treated by moxibustion. Methods： rats were randomly divided into normal group, model group, stomach meridian group, control point group. Except for the normal group, all the rats were established into the gastric mucosa injury model by cold restrain stress. Gastric mucosal injury index in rats were observed by light microscopy, the gastric mucosal blood flow volume in rats were tested by the physiological recorder detection. Results： Compared with the model group, the gastric mucosa ulcer index was decreased, the gastric mucosa morphology was significantly improved, gastric mucosal blood flow volume was significantly increased in stomach meridian group （P〈0.01）. The gastric mucosa ulcer index, gastric mucosa morphology and blood flow volume in stomach meridian group were improved significantly than those in control point group （P〈0.01）. Conclusion： Moxibustion on the stomach meridian could increase the gastric mucosai blood flow volume, promote the repair of gastric mucosa injury, and there is a certain correlation between meridians and viscera.

关 键 词：艾灸 急性胃溃疡 形态学 血流量 

分 类 号：R245[医药卫生—针灸推拿学]