X综合征冠状循环内血浆内皮素浓度变化  

Changes of plasma endothelin levels in coronary circulation in patients with syndrome X

作　　者：章渭方[1] 陈君柱[1] 徐勤[1] 朱建华[1] 张芙荣[1] 

机构地区：[1]浙江大学医学院附属第一医院,杭州310013

出　　处：《中华心血管病杂志》2001年第3期158-159,共2页Chinese Journal of Cardiology

摘　　要：目的　探讨X综合征患者中冠状血管内皮功能的变化。方法　采用心房起搏术 ,观察X综合征患者 (n =8)冠状静脉窦血浆内皮素浓度水平 ,同时与年龄、性别相匹配的健康人 (n =6 )作对照。结果　X综合征组在整个试验过程中 ,冠状静脉窦血浆内皮素浓度明显增加 (P <0 .0 5 ) ;并且在不同时点间的浓度均不同 (P <0 .0 5 )。结论　X综合征患者冠状循环内血浆内皮素浓度增高 。Objective To study the relationship between vascular endothelial function and syndrome X. Methods Using atrial pacing techniques, the changes of endothelin concentration in coronary circulation were measured in 8 patients with syndrome X and 6 age matched normal subjects. Results In the syndrome X group, the changes of plasma endothelin were greater than those of the normal controls ( P <0.05). Conclusion The increase of plasma endothelin in coronary circulation in patients with syndrome X may suggest the presence of endothelial dysfunction.

关 键 词：X综合征 心绞痛 冠状循环 血浆内皮素 

分 类 号：R442.8[医药卫生—诊断学]