急性心肌梗死患者入院时血清肌钙蛋白Ⅰ对预后的影响  

Prognostic significance of serum cardiac troponin I at admission in patients with acute myocardial infarction

作　　者：张铸[1] 苏恩本[1] 张寄南[1] 杨志健[1] 曹克将[1] 马文珠[1] 

机构地区：[1]南京医科大学第一附属医院心血管病研究所,210029

出　　处：《江苏医药》2001年第4期265-266,共2页Jiangsu Medical Journal

基　　金：江苏省社会发展基金! (B5 972 0 8) ;江苏省科委社会发展基金! (BS980 39)

摘　　要：目的　探讨入院时血清心肌肌钙蛋白I(cTnI)水平对急性心肌梗死 (AMI)预后的影响。方法　 10 5例AMI患者在入院时取静脉血作血清cTnI浓度检测 ,按急性胸痛发作至入院时间的不同将病人分组 ,比较各组内存活与死亡病人的血清cTnI浓度。结果　 0～ 3、～ 6、～ 12小时组内死亡病例入院时血清cTnI浓度均明显高于存活病例 (P值均 <0 0 5 )。Objective To assess the prognostic significance of serum cardiac troponin I (cTnI)concentration at the point of admission in patients with acute myocardial infarction.Methods Serum samples of 105 patients with established AMI were collected at admission for measuring cTnI and were grouped according to the intervals between the onset of chest pain and admission.Results In 0～3、～6 and ～12 hours groups,the serum cTnI concentrations in those who died after admission were significantly higher than those who survived (all P< 0 05).Conclusions The higher serum cTnI concentration at admission in patients of AMI was associated with the increased risk of subsequent cardiac death during hospitalization.

关 键 词：急性心肌梗死 血清肌钙蛋白Ⅰ 预后 

分 类 号：R542.220.7[医药卫生—心血管疾病]