肉豆蔻属植物化学成分和药理活性研究进展  

Advances of chemical constituents and pharmacological activities of Myristica genus

作　　者：张勇[1] 张娟娟[1] 康文艺[1] 闫文义[1] 

机构地区：[1]河南大学中药研究所,河南开封475004

出　　处：《中国中药杂志》2014年第13期2438-2449,共12页China Journal of Chinese Materia Medica

基　　金：河南省科技厅重点攻关项目(132102310261)

摘　　要：肉豆蔻科肉豆蔻属植物全球约有120余种,分布于南亚,从玻利尼西亚西部、大洋洲、印度东部至菲律宾。国内外学者已从该属植物中分离得到164个化合物,其中大部分是木脂素,此外还包括苯丙素、黄酮和酚类成分等,具有抗菌、抗炎、抗氧化、抗癌、降血糖、保肝等生物活性。该文总结了该属植物的化学成分和药理活性研究进展,为综合利用与深入开展该药用植物资源提供参考依据。The genus Myristica （Myristicaceae） consists of 120 species, which were distributed in South Asia, from west Polynesia, Oceania, eastern India to the Philippines. Phytochemical studies showed that 164 compounds including a majority of lignans, along with phenglpropanoids, flavonoids and phenolics, have been isolated from this genus, which exhibited anti-microbial, anti-inflammatory, anticancer, hyperglycemic and hepatic protective activities. This article summarizes research progress of the chemical compositions and their pharmacological activities from this genus, which could provide reference for the in-depth development and utilization of the Myristica plants.

关 键 词：肉豆蔻属 化学成分 药理活性 研究进展 

分 类 号：R284[医药卫生—中药学] R285[医药卫生—中医学]