松针提取液对实验性高脂血症及脂质过氧化作用的影响  

Effects of the Liquid Pine Needle Extract on Hyperlipemia and Lipid Peroxidation in Rabbits

作　　者：王焰山 张自文 黄晓萍 蒋汝刚 罗德生[2] 胡宗礼[2] 郑红花[2] 章春风[2] 

机构地区：[1]湖北咸宁卫生学校,湖北437100 [2]湖北咸宁医学院,湖北431700

出　　处：《北京中医药大学学报》2001年第2期35-36,共2页Journal of Beijing University of Traditional Chinese Medicine

基　　金：咸宁市科委课题! (No .0 0 2 3 )

摘　　要：经 8周高脂乳剂饲养后 ,选高脂血症造模成功的家兔 1 5只 ,随机分为对照组、松针提取液小剂量治疗组 (实验Ⅰ组 )、松针提取液大剂量治疗组 (实验Ⅱ组 )。取血测TG、TC、MDA含量和SOD活性及总抗氧化活力。结果动物经松针提取液治疗后 ,血TC及MDA含量降低 ,SOD活性及总抗氧化活力升高 ,与对照组比较 ,治疗Ⅱ组的降脂作用和抗氧化能力更显著。结论 :松针提取液对高脂血症有较强的降脂和抗氧化作用。Rabbits with hyperlipidemia successfully induced by feeding hyper lipidic emulsion for 8 weeks were randomly divided into the control group, treating group I (treated with a small dose of the liquid pine needle extract) and treating group II (treated with a large dose of the extract). A certain volume of blood was drawn from the rabbits to determine the levels of TG, TC, MDA, and SOD activity, and total anti oxidizing capacity in the serum. The results showed that after the treatment with the liquid pine needle extract, the levels of TC and MDA were lower, and SOD activity and total anti oxidizing capacity were higher in both treating groups; and compared with the control group, the extract showed stronger effects in treating group Ⅱ. It can be concluded that the extract has fairly strong effects of reducing blood lipid and resisting oxidization.

关 键 词：高脂血症 松针提取液 脂质过氧化 实验研究 

分 类 号：R285.5[医药卫生—中药学]