颈椎前路三节段融合与置换混合术的力学特性  

Biomechanical characteristics of a three-level cervical disc hybrid construct:An in vitroinvestigation

作　　者：刘伟强[1,2] 吕聪伟[1,3] 蒲婷[3] 颜滨[4] 廖振华[2] 

机构地区：[1]清华大学生物医学工程系,北京100084 [2]深圳清华大学研究院,深圳518057 [3]清华大学深圳研究生院,深圳518055 [4]深圳市第二人民医院,深圳518049

出　　处：《清华大学学报（自然科学版）》2014年第5期685-689,共5页Journal of Tsinghua University(Science and Technology)

基　　金："十二五"国家科技支撑计划资助项目(2012BA118B05)

摘　　要：为研究人体颈椎三节段混合手术后手术节段与相邻节段的运动规律,对7具人体颈椎标本先实施C4-C5前路人工椎间盘置换,再实施C3-C4和C5-C6两节段椎间盘切除术后颈前路植骨融合固定,利用材料力学试验机和非接触式光学测量系统测量各节段的运动信息,比较三节段混合组与完整组、单节段置换组的体外生物力学特性,分析三节段混合术与课题组前期三节段融合术(限制型、滑动型)运动保留能力。结果表明:三节段混合术保留生理活动度能力明显优于三节段融合术(无论限制型或滑动型固定板)。This article describes the rules of motion of a human cervical disc after a 3-level hybrid construct.7cadaveric cervical spines（C2-T1）were initially tested in intact condition.Then,all patients had a 1-level（C4-C5）total disc replacement（TDR）followed by a 2-level（C3-C4and C5-C6segments）anterior cervical discectomy and fusion（ACDF）.The movement differences among the 3-level hybrid construct,the intact disc and the 1-level TDR were compared with the 3-level hybrid construct and previous 3-level fusion data（dynamic and static plating systems）.The comparisons show that the 3-level hybrid construct performs better than3-level fusion.

关 键 词：人工颈椎间盘 颈椎前路融合板 生物力学 混合手术 

分 类 号：R318.19[医药卫生—生物医学工程]