心脏局部血管紧张素Ⅱ介导运动心脏重塑的机制  

Mechanism of Exercise- induced Cardiac Remodeling by Local Angiotensin Ⅱ

作　　者：余启政[1] 李欣[1] 

机构地区：[1]成都大学体育学院,四川成都610106

出　　处：《成都体育学院学报》2014年第7期71-75,85,共6页Journal of Chengdu Sport University

基　　金：四川省教育厅2013年度科研项目;(13ZB0340);成都大学校基金项目(项目编号:2012ZJZ01)

摘　　要：文章通过文献法对运动心脏重塑概念、机制相关信号通路的最新研究进展进行了总结,重点对心脏血管紧张素II与运动心脏重塑的关系进行探讨。在此基础上,认定心脏局部血管紧张素II是维护心脏结构和功能稳定的重要因素,是运动心脏重塑的重要介质,而运动心脏重塑存在生理性变化和病理性变化两种情况,即运动性心肌肥大处于完全的生理性肥大和病理性肥大之间的灰色地带。This paper adopts the method of literature to summarize the latest research development in exercise - induced cardiac remodeling concept and the mechanism - related signal pathways with the focus on the research of the relationship between heart angiotensin Ⅱ and cardiac remodeling. On this basis, it is decided that the heart local angiotensin Ⅱis one of the important factors to stabilize cardiac structure and function and also an important medium of sport cardiac remodeling. Exercise - induced cardiac remodeling demonstrates physiological and pathological changes, namely the exercise -induced myocardial hypertrophy is situated in a fully grey area between physiologic hypertrophy and pathologic hypertrophy.

关 键 词：局部血管紧张素Ⅱ 运动心脏 心脏重塑 

分 类 号：G804.2[文化科学—运动人体科学]