不同种类刺激声对国人正常青年人群眼肌前庭诱发肌源性电位的影响  

Ocular vestibular evoked myogenic potential elicited by different types of stimulus among normal young Chinese people

作　　者：杨引通[1,2,3] 许珉[1,2] 张青[1,2] 张睿[1,2] 陈彦飞[1,2] 

机构地区：[1]西安交通大学医学院第二附属医院耳鼻咽喉头颈外科分院 [2]西安交通大学医学院第二附属医院耳病研究所,西安710004 [3]西安市第四医院耳鼻咽喉科,西安710004

出　　处：《临床耳鼻咽喉头颈外科杂志》2014年第13期948-952,共5页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

基　　金：科技部“十一五”科技支撑计划项目(No:2007BAI18B13);国家自然科学基金(No:3013300/G170703);中央高校基本科研业务费专项资金(No:2012jdhz13);陕西省国际科技合作重点项目(No:2013KW-28);西安市科技攻关项目[No:SF1315(1)];西安交通大学医学院第二附属医院新技术新疗法基金(No:2011015)

摘　　要：目的:观察不同种类刺激声对中国正常青年人群气导声刺激诱发的眼肌前庭诱发肌源性电位(ACS-oVEMP)的影响。方法:选择22例正常人为研究对象,分别采用500Hz tone brust、125Hz tone burst和Click作为诱发刺激声进行双耳(44耳)ACS-oVEMP检测,观察和比较ACS-oVEMP波形的引出率、阈值、nⅠ潜伏期、pⅠ潜伏期、nⅠ-pⅠ波间期、振幅及耳间对称性情况。结果:500Hz tone burst诱发的ACS-oVEMP引出率为100%(44/44),125Hz tone burst的引出率为40.9%(18/44),Click的引出率为29.6%(12/44)。500Hz tone burst与其他2组间引出率比较差异有统计学意义(P<0.05);500Hz tone burst的振幅最大[(7.3±5.5)μV],与125Hz tone burst[(3.8±1.5)μV]和Click[(5.8±1.3)μV]2组间振幅比较差异有统计学意义(P<0.05);其他波形参数比较亦差异有统计学意义。结论:不同刺激声可以对ACS-oVEMP的波形造成影响,500Hz tone burst诱发的ACS-oVEMP引出率最高,振幅最大,波形最易辨认。Objective：To observe waveform differences among ocular vestibular evoked myogenic potentials（ACS-oVEMP）elicited by different types of air conducted sound in normal young Chinese subjects.Method：Twenty-two adult volunteers（44ears）were recruited as research subjects including 12males and 10females aged between 18and 35.Five hundred Hz tone burst,125Hz tone burst and click were employed as stimulus for conventional ACS-oVEMP examinations in bilateral ears of each subject.The response rate,threshold,nⅠlatency,pⅠlatency,nⅠ-pⅠlatency interval,amplitude and inter-aural asymmetry were recorded and compared among groups.Result：The response rate was 100%（44/44）in 500Hz tone burst group,40.9%（18/44）in 125Hz tone burst group and 29.6%（12/44）in click group There were statistical significant differences between the 500Hz tone burst group and the other groups（P〈0.05）.Waveform amplitude was the largest in the 500Hz tone burst group（7.3±5.5）μV than that in the 125Hz tone burst group（3.8±1.5）μV and that in the click group（5.8±1.3）μV,which had statistically significant differences between the former and the later two groups（P〈0.05）.Other waveform parameters presented similar differeces.Conclusion：ACS-oVEMP waveforms could be largely affected by different stimulus.500Hz tone burst was the best stimulus with highest response rate,biggest amplitude and therefore most easily recognizable waveform in ACS-oVEMP examination.

关 键 词：前庭 眼肌前庭诱发肌源性电位 诊断 

分 类 号：R764[医药卫生—耳鼻咽喉科]