负压封闭引流术与灌注冲洗术治疗下肢骨感染疗效比较  

Efficacy comparison of the vacuum sealing drainage technology and the tradition perfusion wash operation in the treatment of the lower limbs infection of bone

作　　者：司佳亚[1] 刘长志[2] 陈新胜[3] 

机构地区：[1]南阳医学高等专科学校第一附属医院骨科二病区,河南南阳473000 [2]南阳市第二人民医院呼吸内科二病区,河南南阳473000 [3]南阳医学高等专科学校第一附属医院重症医学科,河南南阳473000

出　　处：《中华医院感染学杂志》2014年第14期3574-3576,共3页Chinese Journal of Nosocomiology

基　　金：河南省科技厅重点研究基金项目(122300410330)

摘　　要：目的比较负压封闭引流术与传统灌注冲洗术治疗下肢骨感染创面的临床疗效,为骨感染治疗方法的选择提供参考。方法选取210例下肢骨感染的患者为观察对象,随机分为观察组和对照组,各105例,观察组患者进行负压封闭引流术治疗,对照组患者进行传统灌注冲洗术治疗,比较两组患者愈合相关指标;数据采用SPSS19.0进行统计分析。结果观察组患者换药次数、感染控制时间、创面愈合时间、抗菌药物使用时间及住院时间分别为(2.5±1.1)次、(12.5±2.1)、(19.1±1.2)、(6.6±1.6)d及(22.5±2.1)d,均低于对照组的(12.7±2.1)次、(23.1±1.7)、(27.6±1.4)、(15.2±1.4)d及(34.1±2.6)d;治疗后组织愈合病理学评分观察组为(8.2±0.3)分,高于对照组的(4.5±0.1)分;两组比较差异均有统计学意义(P<0.05);观察组二次手术率、复发率及治疗总有效率分别为2.86%、1.90%及94.29%,低于对照组的22.86%、20.0%及71.43%,差异均有统计学意义(P<0.05)。结论负压封闭引流术应用于下肢骨感染创面的修复中,可降低二次手术率和复发率、促进组织愈合,效果优于传统灌注冲洗术治疗。OBJECTIVE To compare the clinical effects of the vacuum sealing drainage technology（VSD）and the tradition perfusion wash operation in the treatment of the lower limbs infection of bone,so as to provide reference for the treatment of infection of bone.METHODS A total of 210cases of patients with the lower limbs infection of bone were selected as research objects and were randomly divided into the observation group and control group,105cases of patients in the observation group did the VSD treatment,105cases of patients in the control group did the tradition perfusion wash operation.The healing related indicators of the two groups were compared.SPSS19.0software was used for statistical analysis.RESULTS Of the observation group,the switching frequency was（2.5±1.1）time,which was lower than that of the control group（12.7±2.1）time;the infection control time was（12.5±2.1）d,which was lower than that of the control group（23.1±1.7）d;the healing time was（19.1±1.2）d,which was lower than that of the control group（27.6±1.4）d;the antibiotic use time was（6.6±1.6）d,which was lower than that of the control group（15.2±1.4）d;the total length of hospital stay was（22.5±2.1）d,which was lower than that of the control group（34.1±2.6）d;the pathology score for tissue healing after the treatment was（8.2±0.3）,which was higher than that of the control group（4.5±0.1）,the differences were significant（all P〈0.05）.In the observation group,3cases of patients did secondary surgery,the secondary surgery percentage was 2.86%,which was lower than those in the control group was 22.86%;2cases of patients reappeared,the recurrence rate was 1.90%,which was lower than those in the control group was 20.0%,the difference was significant（P〈0.05）.In the observation group,99cases of patients treated effectively,the total effective rate was 94.29%,which was higher than that of the control group 71.43%,comparative difference was significant（P〈0.05）.CONCLUSION The VSD technology in t

关 键 词：负压封闭引流术 传统灌注冲洗术 下肢骨感染 

分 类 号：R681.8[医药卫生—骨科学]