高原地区氧合液的研制及意义  

THE STUDY AND USAGE OF OXYGENATED SOLUTIONS AT HIGH ALTITUDE

作　　者：杜智敏[1] 刘崇礼[1] 李焕锡 余忠江 

机构地区：[1]解放军第22医院

出　　处：《高原医学杂志》1995年第1期48-50,共3页Journal of High Altitude Medicine

摘　　要：本文在高原地区借助器械对临床常用静脉液体进行氧合，观察氧合前后液体中氧含量变化，为临床采用氧合液纠正低氧血症提供理论依据。结果：①氧合液中氧含量是非氧合液的３．７－７．４倍，平均５．３６倍，前后比较均Ｐ＜０．０１，有非常显著差别；②氧合时提高氧流量，液体中氧含量上升，但４升／分后上升不明显；③延长氧合时间虽氧含量增加，而５分钟已能达到较高值；④氧合液敞口静置随时间延长其氧含量下降。提示：临床常用静脉液体均能氧合，氧合后液体均能用于纠正低氧血症，以５～１０％葡萄糖，平衡盐，生理盐水较好。氧合时间５分钟，氧流量４升／分，氧合液应尽快应用。n order to treat hypoxemia,the solutions for intravenous usage were oxygenated at high alti-tude and the changes of oxygen content (OC)were measured before and after oxygenation.The re-sults showed that the OC of oxygenated solution(OS)was 5.36(3.7～7.4)times as high as that ofnon-oxygenated solution.The OC of the OS increased as oxygen flow which contacted with thesolutions increased,but the OC would remain stable when the oxygen flow reached to 4 liters per-minute.The OC of the OS in uncovered bottle decreased gradually.It was also found that the so-lutions of 5-10%glucose,balanced natrium and normal saline were oxygenated better than othersolutions.Theibest oxygen time and oxygen flow were 5 min,and 4 liters per min The oxygenatedsolutions should be used soon after oxygenation.

关 键 词：高原地区 氧合液 研制 高山病 低氧血症 

分 类 号：R944.9[医药卫生—药剂学] R594.305[医药卫生—药学]