特种功能精细陶瓷对兔红细胞变形性的影响及机理  

The Effect and Its Mechanism Inquiry of Functional Fine Ceramics on Rabbits' Erythrocytic Deformability

作　　者：沈羡云[1] 吴进前[2] 董颖[1] 田杰谟[2] 陈建和[1] 孟京瑞[1] 

机构地区：[1]航天医学工程研究所,北京市100094 [2]清华大学北京市精细陶瓷实验室

出　　处：《中国微循环》2001年第1期33-35,共3页Journal of Chinese Microcirculation

摘　　要：目的探讨特种功能精细陶瓷对“血瘀证”兔血红细胞变形性的影响及机理。方法用激光衍射仪测定0～1000s-1 切变率下兔红细胞变形性DI-R曲线和应力松弛DI -T曲线 ,观察红细胞力学特性 ;采用荧光分光光度计测量经特种功能精细陶瓷温育后兔血液的荧光偏振度 ,观察其红细胞膜流动性。结果与对照组相比 ,在特种功能精细陶瓷作用下 ,兔红细胞变形性得到明显提高(P<0.001),红细胞膜流动性明显改善(P<0.001)。结论特种功能精细陶瓷可增加“血瘀证”兔血红细胞变形性 ,其机理是增加细胞膜的力学特性。Objectve To observe the effect of functional fine ceramics (FFC) on blood stasis rabbits' erythrocytic deformability and inquire into its mechanism. Methods To observe the change of erythrocytic mechanical property, Laser Diffractive Analyzer was used to test the rabbits' erthrocytic deformability DI-R curve, and stress relaxation, DI-T curve during the shear rate of 0-1000S-1. Furthermore, to observe the erythrocytic membranous fluidity. Fluorescent Spectrometer was used to test the degree of fluorescent polarization of rabbits' blood warm-cultivated with the FFC powder. Results The FFC could enhance the erthrocytic deformability and improve the membranous fluidity, compared with the control group, the differences were significant (P<0.001). Conclusion The FFC could promote blood stasis rabbits' erythrocytic deformability, its mechanism is the increase of erythrocytic mechanical property, viscoelasticity and membranous fluidity.

关 键 词：功能精细陶瓷 兔 红细胞变形性 生物波谱 

分 类 号：R331.141[医药卫生—人体生理学]