凉血活血汤治疗寻常性银屑病临床观察及TNF-α水平检测  

Clinical Efficacy and Serum TNF-α Testing of LXHXT Decoction in the Treatment of Psoriasis Vulgaris

作　　者：王萍[1] 张芃 李伟凡[1] 刘清[1] 周冬梅[1] 邓新荣[3] 张志礼[1] 

机构地区：[1]北京中医医院皮肤科,北京100010 [2]北京崇文中医医院 [3]北京市中医研究所

出　　处：《中国皮肤性病学杂志》2001年第2期90-91,共2页The Chinese Journal of Dermatovenereology

摘　　要：目的 探讨中药凉血活血汤治疗寻常性银屑病疗效。方法应用凉血活血汤对１４０例寻常性银屑病患者进行临床治疗观察，用放射免疫法检测部分患者血清肿瘤坏死因子（ＴＮＦ－ａ）水平。结果凉血活血汤总有效率为 ８６．４３％，与对照组差异无显著性（Ｐ＞０．０５），患者血清ＴＮＦ－ａ水平疗后降低。结论凉血活血汤是治疗银屑病的有效方剂。疗后患者血清ＴＮＦ－ａ水平有所下降。Objective To evaluate the efficacy of LiangXueHuoXueTang (LXHXT ) decoction in the treatment of psoriasis vulgaris. Methods Lesions and serum level of tumor necrosis factor-α(TNF-α) of patients with psoriasis were compared before and after treatment with LXHXT decoction. Results The total effective rate of LXHXT was 86. 3 %, no significant difference as compared with that of control group. Serum level of TNF-α of patients improved significantly after treatment. Conclusion Psoria- sis vulgaris responds to LXHXT decoction, the mechanism of Which seems to be mediated by TNF-α.

关 键 词：寻常性银屑病 肿瘤坏死因子 凉血活血汤 治疗 

分 类 号：R758.630.5[医药卫生—皮肤病学与性病学]