稳定期中重度慢性阻塞性肺疾病患者运动能力影响因素分析  

Determinants of exercise capacity in patients with chronic obstructive pulmonary disease (COPD)

作　　者：郭忠良[1] 蔡映云[2] 梁永杰[1] 朱蕾[2] 董鹤嘉[2] 

机构地区：[1]上海市东方医院,上海200120 [2]上海医科大学中山医院

出　　处：《现代康复》2001年第3期38-39,共2页Modern Rehabilitation

摘　　要：目的探讨中重度慢性阻塞性肺疾病 (COPD)患者运动能力的影响因素。方法 30例稳定期中重度 COPD患者，运动前均进行常规肺功能检查、血气分析和生命质量问卷调查。运动过程中监测胸腹呼吸运动之和与潮气容积之比 (TCD/VT）。结果相关分析显示，反映最大运动能力的各指标与一氧化碳弥散量占预计值比、残 /总百分比、用力肺活量、第一秒用力呼气容积、最大呼气流速和静息时动脉氧分压均有较强的相关性；与生命质量评分 VEmax和 VTmax均显著相关。结论中重度 COPD患者运动时通气限制是影响运动能力的重要因素，最大运动能力下降与基础肺功能损害特别是弥散障碍有关；生存质量下降可显著影响患者的运动能力。： Objective To evaluate the factors affecting exercise ability of patients with moderate to severe chronic obstructive pulmonary disease(COPD).Methods Rutine examination of lung function,analysis of blood gas and health－ related quality of life(HRQoL) were performed before exercise in 30 patients.The ratio of thoracoabdominal motion to votile volume(TCD/VT)was monitored during exercise.Results Revelant analysis indicated indeies responed to maximal exercise capacity were closely related to the ratio of the amount of co2 diffused to expected value,resident volume/total volume,FEV1,FVC,PEFR and resting PaO2,VE,VT.Conclusion Restriction of ventilation is a main factor affecting exercise capacity of patients with moderate to severe COPD.Basic pulmonary impairment and the decrease of HRQoL also affect patient's exercise capacity.

关 键 词：慢性阻塞性肺疾病 运动试验 常规肺功能 生存质量 胸腹矛盾呼吸 

分 类 号：R563[医药卫生—呼吸系统]