头孢菌素类药物致过敏性休克148例分析  

Analysis of 148 cases with allergic shock induced by cephalosporins

作　　者：张子滇[1] 陈珊 

机构地区：[1]苏州市第二人民医院,江苏苏州215002 [2]苏州市第三人民医院,江苏苏州215007

出　　处：《药物不良反应杂志》2001年第1期25-27,共3页Adverse Drug Reactions Journal

摘　　要：目的:调查了解头孢菌素类药物的不良反应情况。方法:本文就我们遇到的病例及1986年～2000年6月国内文献报道148例头孢菌素类药物所致严重过敏性休克病例进行综合分析。结果:头孢菌素类药物过敏反应来势凶险,死亡率高,提请临床应用时提高警惕,并就抢救及皮试等问题进行探讨。Objective: To investigate the adverse reactions of cephalosporins. Methods: 148 cases with allergic shock were collected and analysed mostly through Chinese literature retrieval of 1986 - 2000 in addition to a few patients of our hospital. Results: The shock appeared immediately after the drug administration in 66 cases with a severe nature and death followed if the first aid delayed. Conclusion: The treatment of shock and the skin test of drug were discussed. More attention should be attached to the shock associated with cephalosporins.

关 键 词：头孢菌素类药物 过敏性休克 给药途径 

分 类 号：R593.1[医药卫生—内科学]