间甲酚催化烷基化合成2,3,6-三甲基苯酚  

Synthesis of 2,3,6-Trimethylphenol by Catalytic Alkylation of m-Cresol with Methanol

作　　者：姚宪法[1] 韩红[1] 吴西宁[1] 

机构地区：[1]西北化工研究院,陕西西安710600

出　　处：《石油化工》2001年第1期13-16,共4页Petrochemical Technology

摘　　要：采用自行研制开发的新型铁系复合氧化物催化剂 ,以间甲酚为原料 ,甲醇作甲基化剂 ,在固定床管式反应器中进行催化反应 ,一步合成 2 ,3,6 -三甲基苯酚 ,考察了温度、空速及原料配比对反应的影响。结果表明 ,在LHSV 0 .8h- 1 、反应压力 0 .2MPa、温度 36 0℃、间甲酚 /甲醇 /水摩尔比为 1/6 /2的条件下 ,间甲酚的单程转化率为 99 89% ;2 ,3,6 -三甲基苯酚选择性为 90 80 %WT5BZ]2,3,6-trimethylphenol which is useful as intermediates for vitamin E and pesticides was prepared by vapor-phase methylation of m -cresol with methanol in a fixedbed tube reactor in the presence of a metal oxide catalyst The influence of temperature,space-velocity and feed molar ratio on the yield of 2,3,6-trimethylphenol was examined The synthesis process was also described in detail The results show that the catalysts have higher reactivity and selectivity The conversion of m -cresol is 99 89%,the selectivity of 2,3,6-trimethylphenol is 90 80% [WT5HZ][

关 键 词：间甲酚 三甲基苯酚 甲基化 催化 烷基化 

分 类 号：TQ243.12[化学工程—有机化工]