一所山区学校流行性腮腺炎暴发调查和应急接种效果评价  

Investigation on a Mumps Outbreak and Evaluation on Emergent Vaccination Effect at a School of a Mountain Village

作　　者：徐福根[1] 童卫星 闻洪根[1] 陈月光[1] 陈康凯[1] 李安乐[1] 许向军 

机构地区：[1]浙江省杭州市疾病预防控制中心,310006 [2]浙江省临安市卫生防疫站

出　　处：《预防医学文献信息》2001年第2期113-114,137,共3页Liferatue and Information On Preventine Medicine

摘　　要：[目的 ]调查疫情 ,控制暴发 ,评价应急接种效果。 [方法 ]开展暴发调查 ,核实诊断 ;对全校无流行性腮腺炎(流腮 )病史的学生应急接种流腮疫苗 ,并测定抗体效价。 [结果 ]疫情持续约 4个月 ,罹患率全校学生为 2 7 47% ,寄宿生高于走读生 (P <0 0 1) ;检测病人 2 3例 ,抗体滴度≥ 1∶6 4的占 6 5 2 2 % ;应急接种后 ,接种者的抗体阳转率和GMRT分别为 48 5 7% (17/35 )和 2 8,抗体滴度≥ 1∶6 4者占 11 76 % ;应急接种后 17d暴发终止。 [结论 ]这是一起由于传染源输入、延误防制措施、居住拥挤和密切接触引起的山区学校流腮暴发 。Objective]To survey epidemic situation,control outbreak and evaluate emergent vaccination effect [Methods]Outbreak survey and verified diagnosis were carried out All students without mumps history were emergently inoculated with mumps vaccine Mumps antibody was measured by haemagglutination inhibition test [Results]Epidemic situation lasted about four months The attack rate of mumps in all students was 27 47% The rate in the resident students was significantly higher than that in the non resident students(P<0 01) Sera from 23 patients were detected The percentage of HI antibody titers≥1∶64 was 65 22% HI antibody positive seroconversion rate and GMRT of the vaccinees after emergent vaccination were 48 57%(17/35) and 2 8 respectively Proportion of HI antibody titer ≥1∶64 accounted for 11 76% The outbreak was stopped within 17 days after emergent immunization [Conclusions]This mumps outbreak at a school of a mountain village is due to import of infection source,delay of control measure, crowded living condition and close contact The emergent vaccination with mumps vaccine is efficient

关 键 词：流行性腮腺炎 暴发流行病学 应急接种 评价 

分 类 号：R512.101[医药卫生—内科学]