鹰爪种子化学成分的研究  

STUTIES ON THE CHEMICAL CONSTITUENTS OF THE SEEDS FROM ARTABOSTRYS HEXAPETALUS (ANNONACEAE)

作　　者：余竞光[1] 李彤梅[1] 孙兰[1] 罗秀珍[1] 丁卫[1] 李德宇[1] 

机构地区：[1]中国医学科学院,中国协和医科大学药用植物研究所,北京100094

出　　处：《药学学报》2001年第4期281-286,共6页Acta Pharmaceutica Sinica

基　　金：国家自然科学基金资助项目! (2 95 72 0 87)

摘　　要：目的　研究药用植物鹰爪Artabotryshexapetalus (L .f.)Bhandari的化学成分。 方法　利用各种色谱技术进行分离纯化 ,根据化合物的理化性质和光谱数据进行结构鉴定。结果　从鹰爪种子分得 4种木脂素 :异洋商陆素A(isoamericaninA ,1)、异洋商陆醇A (isoamericaninolA ,2 )、洋商陆素B (americaninB ,3)、鹰爪木脂醇(artabotrycinol,4) ,以及 (R) 鹰爪三醇 [(R) artabotriol,5 ]、棕榈酸 ( 6 )、β 谷甾醇 ( 7)和胡萝卜苷 ( 8)等。 结论　鹰爪木脂醇 ( 4)和鹰爪三醇 ( 5 )为新化合物 ,其余AIM To study the chemical constituents of the seeds from Artabotrys hexapetalus (L.f.) Bhandari (Annonaceae). METHODS Various chromatographic techniques were used to separate and purify the constituents. Their structures were elucidated on the physico-chemical properties and spectral data. RESULTS Eight compounds were isolated from the seeds of A.hexapetalus . They were identified as four neolignans: isoamericanin A (1), isoamericanol A (2), americanin B (3) and artabotrycinol (4), a semiterpenoid: ( R )-artabotriol (5) and others: palmitic acid (6), β-sitosterol (7) and daucosterol (8). CONCLUSION Artabotrycinol (4) and ( R )-artabotriol (5) are new compounds. Three other neolignans were isolated from this plant for the first time.

关 键 词：鹰爪 番荔板科 鹰爪木脂醇 (R)-鹰爪三醇 异洋商陆素A 异洋商陆醇A 洋商陆素B 中药 化学成分 

分 类 号：R284.1[医药卫生—中药学]