TrkB在成年猫脊髓的表达  

The Immunohistochemical Study on the Distribution of TrkB in Spinal Cord of Adult Cats

作　　者：陈彦红[1] 王廷华[1] 冯忠堂[1] 

机构地区：[1]昆明医学院神经科学研究所,昆明650031

出　　处：《昆明医学院学报》2001年第1期25-26,共2页Journal of Kunming Medical College

基　　金：云南省自然科学基金!资助 (99C0 0 0 6R)

摘　　要：采用免疫组织化学方法探讨trkB在成年猫脊髓的分布 .结果 :trkB的免疫阳性反应物主要分布于脊髓灰质腹角、中间带及背角深浅部的神经元 ,胞浆染色 .表明成年猫脊髓神经元含有trkB 。TrkB was designated as the functional receptor of brain derived neurotrophic factor. In these study, we investigated the distribution of trkB-like immunoreactivity(trkB-IR) in spinal cord of adult cats using specific antiserum for trkB by immunohistochemistry ABC method. The results were as following: trkB-IR was mainly distributed in neurons of spinal cord including ventrolateral horn, intermedius are and dorsal horn. The subcellular localization of positiveproduct was mainly in cytoplasm. Our results provided morphological evidence on the distribution of trkB in spinal cord of adult cats. It indicated the role of trkB involve in physiological function of spinal cord of adult cat.

关 键 词：猫 脊髓 背根节 免疫组织 化学 TRKB 脊髓损伤 

分 类 号：R338.21[医药卫生—人体生理学] R651.202[医药卫生—基础医学]