深圳市婴幼儿腹泻中肠道腺病毒感染的流行特点调查  

Studies on epidemic feature of enteric adenoviruses infection in feces of infants with diarrhea in Shenzhen

作　　者：何雅青[1] 杨洪[1] 林奕芝 黄福新[1] 

机构地区：[1]深圳市卫生防疫站微生物检验科,518020 [2]深圳市福田区卫生防疫站检验科

出　　处：《中华流行病学杂志》2001年第2期96-98,共3页Chinese Journal of Epidemiology

摘　　要：目的　了解深圳市婴幼儿腹泻患儿肠道腺病毒的感染情况。方法　应用聚合酶链反应技术 (PCR)对 195份婴幼儿腹泻标本进行腺病毒DNA检测 ,并使用RsaⅠ内切酶对扩增产物进行限制性内切酶图谱分析 ,以鉴别肠道腺病毒型别。结果　婴幼儿腹泻标本腺病毒DNA检测的阳性率为13.33% (2 6 / 195 )。肠道腺病毒 40型的感染率为 2 .5 6 % (5 / 195 ) ,肠道腺病毒 41型的感染率为8.2 1% (16 / 195 ) ,其他型别腺病毒的感染率为 2 .5 6 % (5 / 195 ) ,发热是腺病毒感染的特征性的临床表现。结论　肠道腺病毒 40型和 41型是引起深圳市婴幼儿腹泻的重要病原 ,其中又以肠道腺病毒 41型感染为主。Objective To estimate the enteric adenoviruses infection in feces of infants with diarrhea in Shenzhen. Methods All 195 fecal samples of infants were tested by PCR. Amplimers were analysed by Rsa Ⅰ endonucleases and the type of enteric adenovirus identified. Results The positive rate of adenovirus DNA in fecal samples was 13.33 %(26/195) while the prevalence rates of enteric adenovirus type 40, adenovirus type 41 and the other type of adenovirus were 2.56 %(5/195), 8.21 %(16/195) and 2.56 %(5/195) respectively. Fever was the characteristic symptom of adenovirus infection. Conclusion Enteric adenovirus type 40 and 41 were important pathogens which caused infant diarrhea in Shenzhen, with latter the majorty.

关 键 词：肠道腺病毒 感染率 流行病学 婴幼儿 腹泻 

分 类 号：R181.3[医药卫生—流行病学]