脉冲电喷雾现象的初步研究  

Preliminary Research on Pulsed-Electrospray Phenomenon

作　　者：LU Yu 陆宇[2] ZHOU Feng 卞利萍[2] 周峰[2] 孙平[3] 杨原[2] 郭寅龙[4] 余天[4] 

机构地区：[1]Department of Chemistry, Fudan University, [2]复旦大学化学系, [3]复旦大学化学系, 上海 200433 [4]中国科学院上海有机化学研究所,

出　　处：《高等学校化学学报》2001年第4期560-562,共3页Chemical Journal of Chinese Universities

基　　金：国家自然科学基金，中国分析测试协会科学仪器发展基金

摘　　要：A novel pulsed-electrospray device is reported in this paper. With such an apparatus, the observation of the electrospray process under the pulsed high voltage conditions has been successfully made with microscope, oscilloscope and mass spectrometer. By using pulsed spray technique, the sample flow rate can be averagely decreased to ＜100 nL/min. After increasing the frequency of pulsed high voltage, it is hopefully to directly combine this device to time-of-flight mass spectrometer and obtain a great enhancement both in signal-to-noise ratio and in detection sensitivity for mass spectrometry analysis.A novel pulsed electrospray device is reported in this paper. With such an apparatus, the observation of the electrospray process under the pulsed high voltage conditions has been successfully made with microscope, oscilloscope and mass spectrometer. By using pulsed spray technique, the sample flow rate can be averagely decreased to <100 nL/min. After increasing the frequency of pulsed high voltage, it is hopefully to directly combine this device to time of flight mass spectrometer and obtain a great enhancement both in signal to noise ratio and in detection sensitivity for mass spectrometry analysis.

关 键 词：脉冲电喷雾 生物质谱 分析性能 生物大分子 质谱分析 

分 类 号：Q503[生物学—生物化学] O657.63