益气养阴方对阿霉素致大鼠心肌损伤的影响  

Effect of qi boosting & yin nourishing formula on rat′s myocardial damage caused by amycin

作　　者：许占民[1] 王鑫国[1] 张一昕[1] 曹丽静[1] 曹刚[1] 朱长福[1] 李春花[1] 张玉兰[1] 

机构地区：[1]河北医科大学中医学院,石家庄050091

出　　处：《河北中医药学报》2001年第1期1-3,39,共4页Journal of Hebei Traditional Chinese Medicine and Pharmacology

基　　金：河北省卫生厅资助项目!( 980 0 2号)

摘　　要：目的 :观察益气养阴方药对心肌损伤的影响。方法 :采用阿霉素致大鼠心肌损伤模型。结果 :益气养阴方 ( 1 5g/kg、 3 0g/kg)可降低血清MDA、LDH、SGOT水平 ,提高SOD活性 ;心肌透射电镜观察可见大鼠心肌细胞损害减轻。结论Objective:to make observation on the effect of qi boosting & yin nourishing formula on myocardial damage Method:we adopted the model of myocardial damage caused by amycin.Result:qi boosting & yin nourishing formula(1 5g/kg,3 0 g/kg)could reduce the level of MDA,LDH and SGOT in blood serum and improve SOD activity;myocardial TEM showed abated damage of rat′s myocardial cells.Conclusion:qi boosting & yin nourishing formula could protect myocardial damage.

关 键 词：益气养阴方 阿霉素 大鼠 心肌损伤 中医药疗法 

分 类 号：R259.422[医药卫生—中西医结合] R285.5[医药卫生—中医内科学]