定量^(99)Tc^m- MIBI心肌断层显像评估左室重构  

Quantitative evaluation of LVRM by~ (99)Tc^m- MIBI myocardial SPECT imaging

作　　者：孙晓蓉[1] 乔俏[2] 李亚明[1] 韩春启[1] 

机构地区：[1]中国医科大学第一临床学院核医学科,辽宁沈阳110001 [2]中国医科大学84期,辽宁沈阳110001

出　　处：《中国临床医学影像杂志》2001年第1期15-17,共3页Journal of China Clinic Medical Imaging

摘　　要：目的：应用 99Tcm－甲氧基异丁基异腈 (MIBI)心肌断层显像方法对左室重构进行定量评估。材料和方法：对 18例正常人和 57例冠心病 (CHD)患者行 99Tcm－ MIBI心肌断层显像，分析两组间心尖部和中央部纵径比 (LR)和横径比 (TR)及二者之差 (LR－ TR)的差别。结果：病人组 LR和 TR值明显高于正常组，其中陈旧性心梗和心绞痛患者的 LR－ TR值明显高于正常组；病人组 LR和 TR值与缺损计分、缺血面积百分比以及异常节段数明显相关，与冠脉狭窄支数相关性较弱，与左冠状动脉前降支单支的狭窄程度无明显相关。结论：心肌 99Tcm－ MIBI断层显像通过 LR和 TR两种参数的选定，可对左室重构的发生进行定量的评估。Objective: To quantitatively evaluate left ventricular remodeling(LVRM) using 99Tcm－ MIBI myocardial SPECT imaging.Materials and Methods:99Tcm－ MIBI myocardial SPECT imaging was performed in 18 healthy subjects and 57 patients with coronary heart disease,and the ventricular luminal diameters,the total defect scores(TDS)of segments,and the size of ischemic areas were measured.The longitudinal diameters(LD)and transverse diameters(TD)between the apical and equatorial regions were compared,and the difference between LR and TR(LR－ TR)was cauculated.Results: The values of LR,TR in patient group and LR－ TR in patients with old myocardial infarction and in patients with angina pectoris were significantly higher than those in normal subject group;Both LR and TR had significantly positive correlation with the TDS,the size of ischemic areas and the sum of abnormal segments,and had a weak positive correlation with the number of the constrictive coronary artery,but had no significant correlation with the stenosis degree of single coronary artery.Conclusions:By measuring LR and TR,99Tcm－ MIBI myocardial SPECT imaging can be used as a method of quantitative evaluation of LVRM.

关 键 词：腈类 放射性核素显像 左室重构 

分 类 号：R817.4[医药卫生—影像医学与核医学]