磷钼酸催化合成氯乙酸乙酯  

Catalytic synthesis of ethyl chloroacetate with phospho-molybdic acid

作　　者：郑纯智[1] 张国华[1] 王普力 

机构地区：[1]淮海工学院化工系,江苏连云港222005 [2]连云港市环境保护监测中心站,江苏连云港222001

出　　处：《应用化工》2001年第1期30-31,37,共3页Applied Chemical Industry

摘　　要：筛选了氯乙酸与乙醇酯化制备氯乙酸乙酯的催化剂和带水剂 ,并得出了酯化反应的最佳条件 :醇酸比为 3∶1(0 3mol∶0 1mol)、0 5g磷钼酸为催化剂、15ml环己烷为带水剂 ,回流反应 90min ,产率可达 93%。The esterification of chloroacetic acid and ethanol is studied. The proper catalyst and water carrying agent were selected. It has been indicated by results of experiment that proper mole ratio of alcohol to acid is 3∶1(0 3 mol∶0 1 mol), appropriate use level of catalyst phospho molybdic acid is 0 5 g., cyclohexane is suitable water carrying agent which the optimum use level is 15 ml, reaction 90 min in a state of reflux. The maximum yield of ester is 93%.

关 键 词：氯乙酸乙酯 磷钼酸 酯化 催化合成 

分 类 号：TQ225.3[化学工程—有机化工]