利培酮片的一阶导数分光光度测定  

Determination of Risperidone Tablets by First Order Derivative Spectrophotometry

作　　者：刘新泳[1] 付崇铭 刘丽娟[1] 王兴坡[1] 

机构地区：[1]山东大学药学院,山东济南250012 [2]山东精神病医院,山东济南250014

出　　处：《中国医药工业杂志》2001年第4期174-176,共3页Chinese Journal of Pharmaceuticals

摘　　要：采用一阶导数分光光度法测定利培酮片的含量。以甲醇为溶剂 ,浓度在 5～ 40 μg/ml范围内 ,浓度 C与 2 5 4nm和 2 78.5 nm导数光谱峰谷间的振幅 D呈线性关系 ,r=0 .996 6。平均回收率为 99.91% ,RSD为 0 .0 5 %。First order derivative UV spectrophotometry was applied for determination of risperidone tablets. It had good linearity between amplitude values ( D ) and concentrations ( C ) in 5~40 μg/ml in methanol solution, and the average recovery was 99.91% with RSD 0.05%.

关 键 词：利培酮 片剂 一阶导数分光光度计 测定 含量 抗精神病药 

分 类 号：R971.4[医药卫生—药品] R927.2[医药卫生—药学]