肾移植术后环孢素性肝损害的治疗研究  

Study on nephroxicity induced by cyclosprine A

作　　者：刘建平[1] 闫宏亮[1] 王凤华[1] 曲红[2] 

机构地区：[1]中国人民解放军第四军大学吉林军医学院附属医院泌尿外科,吉林吉林132011 [2]吉林市第二人民医院外科,吉林吉林132011

出　　处：《吉林医学》2001年第2期92-93,共2页Jilin Medical Journal

摘　　要：目的：为观察山莨菪碱、护肝片加片仔癀治疗肾移植术后环孢素性肝损害的疗效，寻找有效的治疗方法。方法：将３２例肾移植术后环孢索性肝损害患者分为２组，Ａ组：用山莨菪碱治疗；Ｂ组：护肝片、片仔癀治疗。结果：Ａ组２０例中有１８例治愈（占９０％），好转２例（占１０％）；Ｂ组１２例中有４例治愈（占２５％），无效８例（占７５％）。结论：肾移植术后环孢素性肝损害，应用山莨菪碱组治疗效果明显高于护肝片加片仔癀组。Objective To observe the curative effect of anisodamine and Liver-Aid(sugar-coated tablet) plus Pian Zai Huang on nephroxicity induced by cyclosprine A (CsA). Method Thirty-two renal transplant sapients with nephroxicity induced by CsA were randomly divided into two groups. Group A: with the treatment of anisodanmine, group B: with the treatment of Liver-Aid pills and Pian Zai Huang. Results Eighteen cases of patients are cured within twenty cases in group A (occuping ninety percent), 2 cases bocome better (ten percent);four cases are cured within twelve cases in group B(twenty-five percent), 8 cases are of no effect(seventy-five Percent). Conclusion The therapetic effect with the treatment of anisodmine in group A is better than with Liver-Aid pills together with Pian Zai Huang.

关 键 词：肾移植 环孢素 肝损害 手术后 

分 类 号：R595.3[医药卫生—内科学]