皮肤化学美白剂抑制酪氨酸酶活性的研究  

Study on Inhibitory Activity of Lighteners Against Tyrosinase

作　　者：刘宇红[1] 董银卯[1] 李才广[1] 

机构地区：[1]北京工商大学化工学院,北京100037

出　　处：《日用化学工业》2001年第1期21-23,共3页China Surfactant Detergent & Cosmetics

摘　　要：采用化学评价法 ,即通过测定皮肤美白剂对酪氨酸酶的活性抑制率 ,对 9类 13种皮肤美白剂的活性进行了评价与比较。排出了抑制次序 ;绘制了各美白剂浓度与其酪氨酸抑制率关系曲线 ,多数美白剂呈钟形曲线 :得到了各美白剂的ICmax及IC50 ;探讨了酪氨酸酶抑制率与美白效果评价的关系。The activity of thirteen kinds of skin lighteners were evaluated and compared by chemical method,i.e,by detemining inhitory activity against tyrosinase.The order for inhibitory activity against tyrosinase, IC_maxand IC_50were obtained. The diagrams of relation between each lightener concetration and its inhibitory activity were drawn. The relation between activity evaluation of lightener and its value of inhibitory activity against tyrosinase was discussed.

关 键 词：皮肤美白剂 酪氨酸酶 黑色素 酪氨酸活性抑制率 活性 

分 类 号：TQ658.2[化学工程—精细化工]