噪声对血浆中单胺类神经递质含量的影响  

Effect of noise on content of monoamine neurotransmitter in plasma

作　　者：常秀丽[1] 刘书乾[1] 

机构地区：[1]山西医科大学劳动卫生教研室,太原市030001

出　　处：《职业与健康》2001年第4期4-5,共2页Occupation and Health

摘　　要：[目的]观察噪声暴露不同时间对大鼠血浆中单胺类神经递质含量的影响。[方法]将大鼠暴露于100 dB分贝(A)噪声中,在不同暴露时间(1天,7天,21天)采用荧光分光光度法对大鼠血浆中单胺类神经递质去甲肾上腺素(NE)、多巴胺(DA)和五羟色胺(5-HT)的含量进行了测定。[结果]与对照组相比,血浆NE、DA和5-HT在噪声暴露21天后显著升高(P<0.05),而1天,7天变化不明显。[结论]长时间的噪声暴露可引起外周交感神经的激活。[Objective] To obverse the effect of noise on content of monoamine neurotransmitter in rats' plasma in varying time. [Me Rats were exposed to 100 dB (A) noise. The content of monoamine neurotransmitter: Norepinephrine (NE), Dopamine (DA), and 5 droxytryptmin (5 - HT) were monitored after various duration (1 day, 7 days, and 21 days) . [Results] Compared with control grou| contents of plasma NE, DA, and 5 - HT significantly increased after 21 days (p < 0.05). [Conclusion] There may be an excital sympathetic nerve under long - term noise exposure.

关 键 词：噪声 去甲肾上腺素 多巴胺 五羟色胺 

分 类 号：TB53[理学—物理] R135.1[理学—声学]