10200例尿液标本细菌L型培养及药敏试验结果分析  

Analysis of L-bacterial Cultivation and Its Drug Sensitivity with Urine Sample in 10 200 Cases

作　　者：张秋桂[1] 郭思健[2] 

机构地区：[1]南华大学第一附属医院,湖南衡阳421001 [2]湖南医科大学附属湘雅医院,长沙410078

出　　处：《南华大学学报（医学版）》2001年第2期133-135,共3页Journal of Nanhua University(Medical Edition)

摘　　要：目的　探讨泌尿系感染患者尿液细菌L型的病原菌种类及耐药性。方法　采取 10 2 0 0例门诊及住院患者的尿液进行细菌L型培养及药敏试验。结果　分离出细菌L型 2 979株 ,阳性率 2 9.2 % ,分离出菌种 2 2种 ,其中革兰氏阳性菌 2 178株 (占 73.1% ) ,革兰氏阴性菌 80 1株 (占 2 6.9% )。 4种主要病原菌是表皮葡萄球菌、粪肠球菌、大肠埃希氏菌及金黄色葡萄球菌 ,分别占全部检出细菌L型的 2 5.6%、2 0 .5%、17.9%、17.7%。药敏试验显示表葡菌、金葡菌、粪肠球菌共同敏感的药物是万古霉素、呋喃妥因和舒普深 ;4种主要病原菌共同敏感的药物是呋喃妥因 ,其次是舒普深。结论　泌尿系感染患者尿液常规培养加细菌L型培养可提高细菌检测阳性率 ,为临床诊断和抗生素的合理使用提供重要依据。Objective: To explore the parental bacteria of L-form in the urine of the patients with urinary infection and its drug sensitivity .Methods: Cultivation and drug sensitivity test were performed on the urine samples of 10 200 patients with urinary infection. Results:2 979 strains of bacterial L-form were separated out and the positive rate was 29.2% . 22 kinds of parental bacteria were identified,Gram positive bacteria being 2 178 strains (73.1%) and Gram negative bacteria being 801 strains (26.9%).The main four kinds of parental bacteria were S.epidermidis (25.6%),S.faecalis (20.5%),E. coli (17.9%) and S.aureus (17.7%).On the drug sensitivity test ,S. epidermidis,S.aureus and S.faecalis were sensitive to vancomycin,furadantin and cefoperazone,and all of four kinds of bacteria were well sensitive to furadantin,then sensitive to sefoperazone. Conclusions: Cultivation of L-form with sample of urine ,if routinely perormed,can increase the positive rate of bacteria and provide animportant clue to the diagnosis and the rational administration of antibiotics.

关 键 词：细菌L型 尿液 细菌培养 药敏试验 抗药性 

分 类 号：R446.5[医药卫生—诊断学]