针刺治疗震颤麻痹对患者血中LPO和SOD含量的影响  

Effects of Acupuncture Treatment on Blood LPO and SOD Contents in Parkinsonism Patients

作　　者：董晓彤[1] 王双昆[1] 任小群[1] 郁美娟[1] 杨金洪[1] 刘爱华[1] 刘家瑛[1] 陈桂平[1] 王友京[1] 

机构地区：[1]中国中医研究院针灸研究所,北京100700

出　　处：《针刺研究》2001年第1期28-31,共4页Acupuncture Research

基　　金：国家中医药管理局资助项目!(95A1117)

摘　　要：本文观察了针刺治疗震颤麻痹对患者血中LPO和SOD含量的影响 ,结果表明 ,针刺能提高震颤麻痹病人血中超氧化物歧化酶 (SOD)的含量 ,而其中以病程短的病人血中SOD含量升高较为显著 ,同时发现 ,年龄在 60岁以上者及女性病人针刺后血中SOD增长幅度较大。Objective: To observe effects of acupuncture treatment on blood LPO and SOD contents in Parkinsonism patients. Methods: 87 Parkinsonism patients were randomly divided into acupuncture group (n= 59) and medication group (n= 28). Acupoints as Xiaochan point (1.5 cun inferior to Shaohai HT 3), Waiguan (TE 5), Hegu (LI 4), Yanglingquan (GB 34), Taichong (LR 3), Zusanli (ST 36), etc were used and stimulated with uniform reinforcing reducing needling method. The treatment was given once daily, with 10 sessions being a therapeutic course, continuously for 3 courses. Patients in medication group were treated with madopar, sinemet, artane, etc based on the doctor's requirements. Plasma LPO content and SOD content of red blood cells were detected by using thiobarbituric acid via lipid peroxide malonyldialdehyde technique and radioimmunoassay respectively.Results: Results showed that after acupuncture treatment, SOD content increased significantly, particularly in patients above 60 years at age, female patients and the patients with disease duration being less than 3 years in comparison with those under 60 years , male patients and those with disease duration being over 3 years respectively. Conclusion: Acupuncture can function well in preventing Parkinsonism from exacerbation particularly in patients above 60 years old, female patients and those with shorter duration of disease.

关 键 词：震颤麻痹 针刺疗法 超氧化物歧化酶 氧自由基 过氧化脂质 

分 类 号：R277.725[医药卫生—中医学] R246.6