强迫振荡法肺功能测定国人正常值的研究  

Study on Normal Area of Each Parametric in Pulmonary Function Test with Impulse Oscillation(IOS)in Healthy Chinese

作　　者：李征征[1] 邝土光[1] 杨丽[2] 付江媛[2] 王浩彦[1] 柯以恕[1] 张洪玉[1] 

机构地区：[1]北京红十字朝阳医院呼吸疾病研究所,100020 [2]北京红十字朝阳医院综合科,100020

出　　处：《中国误诊学杂志》2001年第5期646-649,共4页Chinese Journal of Misdiagnostics

摘　　要：目的　试找出强迫振荡法肺功能测定国人的正常值范围。方法　随机选取 130名同一居住区不吸烟的健康人 ,先进行常规肺功能检测 ,再对常规肺功能正常者共 75名用强迫振荡法测定肺功能 ,按照欧洲呼吸协会公布的测定要求执行 ;测定指标包括 R(5 - 35 ) Hz粘性阻力 ,X(5 - 35 ) Hz弹性阻力及惯性阻力 ,FRE(共响频率 ) ,Zr(呼吸总阻抗 ) ,Rc(中心阻力 ) ,Rp(周边阻力 )。结果　经统计学处理 ,正态性分布检验可看出 :ZR、FRE、RC、RP以及 R5 - R35均呈正态分布 (P>0 .0 5 ) ,实测值 /预计值 %中 R5 %～R35 % ,除 R2 5 %不呈正态分布 (P<0 .0 5 )外 ,其余均呈正态分布 ;而 X5 - X35、CL、CB、CM则不呈正态分布 (P<0 .0 5 ) ,国外提供的正常预计值与我国健康人实测值的配对 t检验结果 :ZR、R5、R2 0两者间无显著性差异。结论　参数 ZR、R5、R2 0、RC、RP、X5均可作为 IOS测定的主要分析指标并且国外预计值可用于国人 ,但实测值 /预计值 %应定为 :(R5、R2 0 ) <110 % ,FRE为 <15 Hz,R35国外预计值与我国实测值有显著差异 ,建议使用我国正常值 ,实测值 /预计值 %为 <130 %Objective To get the normal area of each parametric in pulmonary function test with impulse oscillation (IOS) and propose diagnosis condition for clinic usage.Methods 130 people without cardiac and pulmonary diseases,no smoking or little smoking,were included in this study.They are all living in the same area.First their ventilation function were tested with flow volume curve,and then 75 normal people without little airway disease were tested in IOS.The parametrics inculde R(5 35)Hz (airway resistance),X(5 35)Hz(airway reactant),FRE(frequency resonant),Zr (Impedance),Rc(centric resistance)and Rp(periphery resistance).Results Most of the parametric such as ZR、FRE、RC、RP and R5 R35,their distributions are normal (P>0.05),and in the parametric of our study such as ZR,R5,R20,R25,R35,X20,X25,X35,their values have no difference with the proposed value of foreigner.Conclusion National people and foreigner,the criterion of diagnosis must be suited for our national people.We suggest the act/pre% of R5,R20,ZR should be less than 110%,and that of R35 less than 130%.

关 键 词：强迫振荡法 肺功能 测定 国人正常值 

分 类 号：R443.6[医药卫生—诊断学]