急性心肌梗塞溶栓治疗相关动脉再灌注对QT离散度的影响  

Effects of reperfusion of infarct-related artery after thrombolytic therapy on QT dispersion in patients with acute myocardial infarction

作　　者：潘光秀[1] 余强[2] 

机构地区：[1]安徽省蚌埠市第三人民医院心电图室,233000 [2]安徽省蚌埠市第三人民医院心内科,233000

出　　处：《淮海医药》2001年第2期94-95,共2页Journal of Huaihai Medicine

摘　　要：目的　探讨急性心肌梗塞 (AMI)患者溶栓治疗相关动脉再灌注对 QT离散度 (QTd)的影响。方法　 6 2例 AMI患者分为溶栓再通组、未通组及非溶栓组 ,测量溶栓前后 QTd,并进行比较。结果　 AMI溶栓前溶栓组 (6 5 .6± 13.9) ms与非溶栓组 (6 3.2± 18.2 ) m s QTd 差异无显著性 (P>0 .0 5 ) ,溶栓治疗再通后 ,QTd明显减小。溶栓未通组及非溶栓组 (4 6 .7± 11.6 ) ms、(4 7.5± 13.2 ) ms,显著高于溶栓再通组 (31.4± 9.4) ms,(P<0 .0 1)。伴心室颤动者 QTd(70 .6± 16 .2 ) ms明显高于不伴心室颤动者 (4 7.9± 13.5 ) ms,(P<0 .0 1)。结论　急性心肌梗塞溶栓治疗相关动脉再灌注后 QTd 明显减小 ,心室颤动的发生率降低。Objective To study the effect of reperfusion of infarct related artery after thrombolytic therapy on QT dispersion(QT d)in patients with acute myocardial infarction(AMI).Methods 62 cases were divided into three groups:thrombolytic and recanalized group,uncanalized group and non thrombolytic group.The QT d was measured before and after thrombolytic therapy and the results were compared.Results The QT d was not significant difference( P >0.05)in patients with AMI before thrombolytic therapy between thrombolytic group [(65.5±13.9) ms] and non thromblytic group[(63.2±18.2)ms].The QT d decreased significantly in thrombolytic and recanalized group.The QT d [(46.7±11.6 ms、47.5±13.2)ms] in uncanalized group and non thrombolytic group were all higher than that in thrombolytic and recanalized group [(31.4±9.4) ms]( P < 0.01 ).The QT d of ventricular fibrillation (VF) group was greatly higher than those without VF[(70.6±16.2) ms,(47.9±13.5) ms]( P < 0.01 ).Conclusion Reperfusion of infarct related artery was associated with the reduction of QT d.and the lower incidence of VF.

关 键 词：心肌梗塞 QT间期离散度 溶栓治疗 动脉再灌注 

分 类 号：R542.22[医药卫生—心血管疾病] R540.41[医药卫生—内科学]