黄芪对健康人群小肠传递时间作用的研究  

Effect of Radix Astragali on the Transmission Small Intestine in Health Subjects

作　　者：乔永芳[1] 江佛湖[1] 孔保圻[1] 

机构地区：[1]上海第二医科大学附属宝钢医院,上海201900

出　　处：《中药新药与临床药理》2001年第3期204-205,共2页Traditional Chinese Drug Research and Clinical Pharmacology

摘　　要：目的 :研究黄芪对肠道运动功能的作用。方法 :采用CM型微量测定仪 ,以 1 8g乳糖为基质作氢气呼吸试验 ,测定 4 0名健康人群服用黄芪 1周前后的小肠传递时间及乳糖吸收的峰值。结果 :4 0名健康人群服用黄芪 1周前后的小肠传递时间分别为 (1 1 6.4 8± 2 4 .57)min和 (1 0 2 .3 8± 1 3 .4 4)min ,P <0 .0 1。乳糖吸收的峰值分别为 (3 5.4 3± 2 1 .2 8)× 1 0 - 6 和 (3 5.3 0± 2 1 .52 )× 1 0 - 6 ,P >0 .0 5。结论 :口服黄芪 1周后 ,不影响小肠对乳糖的吸收 ,但能促进小肠的运动功能。Objective: To observe the effect of Radix Astragali on the transmission time of small intestine(TTSI).Methods: TTSI and the peak value of lactose absorption were determined by hydrogen breath test in 40 healthy subjects a week before and after administration of Radix Astragali. Results: TTSI was 116.48+ 24.57 min and 102.38+ 13.44 min respectively before and after administration (P< 0.01) and the peak value of lactose absorption was (35.43± 21.28)×10 -6 and ( 35.30± 21.52)×10 -6 (P> 0.05).Conclusion: Oral administration of Radix Astragali for one week has no effect on the absorption of the lactose by small intestine,but can promote the movement of small intestine.

关 键 词：黄芪 药理学 氢气呼吸试验 小肠传递时间 中药 

分 类 号：R282.710.5[医药卫生—中药学]