静脉注射胺碘酮治疗心房纤颤快速心室率的临床评价  

Clinical Observation of Intravenous Amiodarone in Patients with Atrial Fibrillation of Rapid Heart Rate

作　　者：李茂亭[1] 吕健[1] 柳景华[1] 马娜[1] 杨俐[1] 

机构地区：[1]北京煤炭总医院心内科,北京100028

出　　处：《中国临床医学》2001年第2期115-116,共2页Chinese Journal of Clinical Medicine

摘　　要：目的 :观察静脉注射胺碘酮治疗心房纤颤并快速心室率的疗效。方法 :36例心房纤颤心室率大于 10 0次 /min者 ,10min静脉推注胺碘酮 15 0mg ,观察 10min ,未转为窦性心律者再次 10min推注 15 0mg ,仍未转复者则以每分钟 0 .5mg～ 1.0mg静脉滴注2 4h ,转为窦性心律者则随时终止滴注。结果 :2 4h内转复为窦性心律者 33人 (92 % )。转为窦性心律时间 10min～ 2 3h ,平均 6 .9h。转复为窦性心律的药物剂量 15 0mg～ 90 0mg ,平均为 40 6mg。无严重心律失常发生 ,未诱发或加重心功能不全。结论 :静脉注射胺碘酮治疗心房纤颤快速心室率疗效确切安全。Objective: The efficacy of intravenous amiodarone in patients of atrial fibrillation with rapid heart rate was evaluated. Methods: 36 patients were injected with amiodarone of 150 mg intravenously within 10 minutes, if no efficacy shown then followed by 150mg again, with still no efficacy, again followed by 0.5-1.0mg/min infusion for 24h. Results: 33 patients returned to sinus rhythm (92%)within 24h,from 10 min to 23h,averaging 6.9h.The dosages were 150mg～900mg, averaging 406mg. There was no severe arrhythmia, and the therapy did not induce or worsen heart dysfunction. Conclusion: Intravenous injection of amiodarone is effective and safe for atrial fibrillation with rapid heart rate

关 键 词：胺碘酮 心房纤颤 快速心室率 静脉注射 并发症 

分 类 号：R541.75[医药卫生—心血管疾病] R541.71[医药卫生—内科学]