用FABMS法研究抗生素柱晶白霉素、4″—酰化螺旋霉素和Shengjimycins的质谱裂解规律  

Study on Mass Spectral Fragmentation of Antibiotics Leucomycins,4′—Acylspiramycins and Shengjimycins by FABMS

作　　者：余志立[1] 孙承航[1] 姜威[1] 黄颉[1] 

机构地区：[1]中国医学科学院中国协和医科大学医药生物技术研究所,北京100050

出　　处：《质谱学报》2001年第1期63-69,共7页Journal of Chinese Mass Spectrometry Society

摘　　要：本文介绍用FABMS法或SIMS法研究抗生素柱晶白霉素、4″—酰螺旋霉素、Shengjimycins的质谱裂解规律。用MS数据和13CNMR(COM ,DEPT)数据鉴别该分子式和结构式。In this paper mass spectral fragmentation of antibiotics leucomycins, 4″—acylspiramycins and Shengjimycins were reported by FABMS and SIMS. The molecular formula and strucure of the antibiotic were idetified by mass data and 13 C NMR(COM DEPT)data. It is a useful method for finding new Antibiotic.

关 键 词：抗生素 柱晶白霉素 4-酰化螺旋霉素 分子式 结构式 FABMS SIMS 质谱裂解规律 Shengjimycins 

分 类 号：R978.1[医药卫生—药品]