检测胆囊结石胆汁中L型细菌的研究及其意义  

L-form bacteriologic assessment of bile from gallbladder in patients with gallstones and cholecystitis and implication

作　　者：韩文胜 石景森[1] 卓健生[2] 杨毅军[1] 李国才[1] 韩玥[1] 焦兴元[1] 

机构地区：[1]西安交通大学第一医院肝胆外科研究室,710061 [2]西安交通大学第一医院检验科,710061

出　　处：《中华实验外科杂志》2001年第3期207-208,共2页Chinese Journal of Experimental Surgery

摘　　要：目的　探讨L型细菌在胆囊结石、胆囊炎发病中的意义。方法　应用高渗培养技术对 13 0例胆囊结石、胆囊炎及 2 0例非胆道疾病的患者胆囊胆汁标本进行普通菌及L型菌联合培养。结果　L型菌总检出率胆囊疾病组为 5 9.2 % ,对照组为 5 .0 % ;胆囊结石胆汁中 ,检出率最高为胆色素类结石 (88.9% ) ,其次为混合性胆石 (80 .0 % )、胆固醇结石 (5 4.8% )和黑色结石(5 0 .0 % ) ;多发结石明显高于单个结石。随年龄增加 ,其感染检出率增高。结论　L型菌感染可能在胆囊结石、胆囊炎发生发展中有重要意义 。Objective To evaluate the role of L form bacteria in the development of gallstone and cholecystitis. Methods A L form bacteriological study was made on 130 patients undergoing elective surgery for gallbladder diseases and 20 subjects with a normal biliary tract as a control group. Results The positive rate of bacterial L form was 59.2 % in benign gallbladder diseases and 5.0 % in the control group. In the bile from gallbladder, the detectable rate for pigment stones was the highest (88.9 %), followed by mixed, cholesterol and black stones (80.0 %, 54.8 % and 50.0 % respectively). There was relationship between the number of gallstone and the L form bacterial positive rate, as well as the age of the patients. Conclusion L form bacterial infection might play a certain role in stone formation in gallbladder and the therapy for L form bacterial infection in the patients with gallstones and chronic cholecystitis should be performed clinically.

关 键 词：L型细菌 胆结石 胆囊炎 胆囊结石 胆汁 

分 类 号：R657.42[医药卫生—外科学]