亮-脑啡肽对中药(痹痛消)镇痛作用的临床研究  

Clinical Study on Analgesic Action of Chinese Medicine (Bitongxiao) to Leucic - eukephalin

作　　者：李金学[1] 向昌菊[1] 刘秀芹[1] 程爱华[1] 王尚全[1] 

机构地区：[1]中国中医研究院骨伤科研究所脊柱二科,北京东直门内北新仓18号100700

出　　处：《中医杂志》2000年第3期148-150,共3页Journal of Traditional Chinese Medicine

基　　金：国家中医药管理局1995年科研课题(95A2519)

摘　　要：用中药痹痛消治疗神经根到颈椎病所致的颈痛33例,以颈复康冲剂所治31例作对照,两组治疗后疼痛积分均较治疗前明显减少(P均<0.01),两组治疗前后疼痛积分的差值比较亦有显著性差异(P<0.05)。气滞血瘀型和风寒阻络型相比较,其镇痛作用未见明显差异。治疗后治疗组血浆中亮氨酸脑啡肽(LEK)含量明显升高(P<0.01),而对照组LEK虽有升高趋势,但与治疗前相比差异无显著性(P>0.05)。33 cases of pain due to neural - root type cervical spondylosis were treated by Bitongxiao. with another 31 cases treated by Jingfukang granule as control. The pain scores in both groups before and after the treatment were markedly decreased (all P <0. 01), so were that of the difference of values between them(P<0. 05). For the analgesic action between the type of qi -stagnation blood - stasis and the type of channel blocked by wind - cold evil, there was no difference. The content of leucic- eukephalin (LEK) in the plasma of the treatment group after treatment increased dramatically (P<0. 01). but that in the control group, though tending to increase, showed no significant difference.

关 键 词：镇痛 脑啡肽 亮氨酸 代谢 痹痛消 中医药治疗 颈椎病 

分 类 号：R285.5[医药卫生—中药学]