铁缺乏对大鼠肝脏及脑组织7种微量元素的影响  

The Influence of Iron Drficiency in 7 kinds Trace Element in Brain and Liver of Rats

作　　者：魏美文[1] 胡瑞梅[1] 张岩[1] 

机构地区：[1]山东医科大学附属医院

出　　处：《微量元素与健康研究》1998年第1期10-11,共2页Studies of Trace Elements and Health

摘　　要：通过铁缺乏动物模型，观察了缺铁性贫血的非贫血期实验组和对照组大鼠肝脏及脑组织７种微量元素的变化。结果表明实验组大鼠肝脏、脑组织总铁和锌含量低于对照组，锰和铜含量高于对照组，硒、镉、铅变化不大。说明铁缺乏除可引起铁减少外，还存在其它元素的代谢紊乱。The Fedeficient animal model was made by feeding them a low Fe content diet to deteet the effect of Fe deficiency in 7 trace element in brain and liver of rats.Two weeks later,the erythrocyte protoporphyrin(FEP)level of the experimental rats was higher than control rats,but the hemoglobin conventration was not significiently affected.In this stage( Fe deficiency without anemia)the Fe content in brain and liver of experimental rats was sighificienthy lower than control rats,Mn was higher.Cu in liver of experimental rat was higer than control rats,but the zinc in brain was lower.Se Cr and Pb had not change.It is suggested that iron deficient rats not only had decreased in iron but had varied in other trace clement,and the line of clinical presence of iron deficience hand related with the variety of other trace element.

关 键 词：铁缺乏症 微量元素 肝脏 脑组织 大鼠 

分 类 号：R591.1[医药卫生—内科学] Q581[医药卫生—临床医学]