米托蒽醌脂质体制备工艺的研究  

STUDY ON THE PREPARATION TECHNIQUES OF MITOXANTRONE LIPOSOMES

作　　者：段逸松[1] 张志荣[1] 

机构地区：[1]四川大学华西药学院,四川成都610041

出　　处：《华西药学杂志》2001年第2期91-92,共2页West China Journal of Pharmaceutical Sciences

摘　　要：目的 :优选米托蒽醌脂质体制备工艺。方法 :以形态、粒径、包封率为指标评价工艺。结果 :逆相蒸发法制备的脂质体粒径小 ,包封率高。结论OBJECTIVE:To present the optimum method of the preparation of mitoxantrone liposomes METHODS:To select the optimum method with morphology,particle size and entrapping efficiency as criterion RESULTS:A sample with small particle size and high entrapping efficiency has been produced with reverse phase evaporation method CONCLUSION:Reverse phase evaporation is the optimum technique

关 键 词：米托蒽醌 脂质体 制备工艺 蒽环类抗生素 

分 类 号：R979.14[医药卫生—药品] R944.1[医药卫生—药学]