肺动脉血栓内膜剥脱术治疗慢性栓塞性肺动脉高压  

Pulmonary thromboendarterectomy in the management of chronic pulmonary thromboembolic hypertension

作　　者：吴清玉[1] 吴永波[1] 王东进[1] 董超[1] 郭少先[1] 

机构地区：[1]中国医学科学院,中国协和医科大学,北京阜外心血管医院心外科,北京100037

出　　处：《中华结核和呼吸杂志》2001年第5期273-275,共3页Chinese Journal of Tuberculosis and Respiratory Diseases

摘　　要：目的　报告肺动脉血栓内膜剥脱术治疗慢性栓塞性肺动脉高压的经验。方法　回顾性总结了连续 8例肺动脉血栓内膜剥脱术的手术要点、围术期处理以及近中期结果。结果　 8例均存活。肺动脉收缩压由术前的 (10 1± 2 4)mmHg降至术后的 (39± 15 )mmHg、动脉血氧分压由 (5 9± 11)mmHg升至 (92± 7)mmHg。动脉血氧饱和度由 (0 89± 0 0 6 )升至 (0 98± 0 0 1) ,均有显著改善。随访显示患者心功能为纽约心功能协会分级标准 (NYHA)Ⅰ级 (3例 )或NYHAⅡ级 (5例 ) ,生活质量明显改善。结论　肺动脉血栓内膜剥脱术是治疗慢性栓塞性肺动脉高压的有效手段。Objective The efficacy of surgical treatment (pulmonary thromboendarterectomy,PTE)in the management of chronic pulmonary thromboembolic hypertension (CTE PH) was reviewed. Methods A retrospective study of 8 patients receiving consecutive PTE in Fuwai cardiovascular hospital was made,with special regard to the operation methods, perioperative management and follow up. Results All survived the operation. As compared with preoperative values,all patients presented with significant improvement of systolic pulmonary artery pressure [(39±15) mmHg versus (101±24) mm Hg],arterial oxygen tension [(92±7) mmHg versus (59±11) mm Hg]and arterial oxygen saturation (0.98±0.01 versus 0.89±0.06). Mid term follow up showed that the cardiac function of the patients fell into NYHA class Ⅰ ( n =3)or Ⅱ ( n =5),with significant improvement in quality of life. Conclusion PTE is effective treatment in the management of CTE PH.

关 键 词：肺血栓栓塞症 血栓内膜剥脱术 肺动脉高压 

分 类 号：R543.2[医药卫生—心血管疾病]