腹部外科疾病并发多器官功能障碍综合征时的中西医结合治疗研究  

Combined treatment of abdominal diseases associated with MODS by traditional Chinese medicine and Western medicine

作　　者：岳茂兴[1] 

机构地区：[1]解放军第306医院,北京100101

出　　处：《创伤外科杂志》2001年第1期12-15,共4页Journal of Traumatic Surgery

基　　金：解放军总装备部卫生局重点科研课题资金资助项目!(NO.965140369)

摘　　要：目的　探索降低腹部外科疾病并发多器官功能障碍综合征 (MODS)患者病死率的中西医结合治疗措施。方法　 (1)提出了短程大剂量联合应用山莨菪碱、地塞米松为主的综合救治方案 ;(2 )整体治疗MODS时 ,在“炎性介质、细菌、内外毒素、微循环、免疫功能、营养代谢、基础疾病、脏器功能”等方面进行兼顾和并治 ,并相应实施 14条具体治疗措施 ;(3)应用“分阶段代谢营养支持”治疗 ;(4 )采用自制的“解毒固本汤”配合治疗。结果　在本组按KnausWA教授MODS的诊断标准确诊为MODS的 118例患者中 ,死亡 5 9例 ,病死率为 5 0 .0 0 %。 118例中应用传统常规疗法 87例 ,死亡 49例 ,病死率为 5 6 .32 % ;采用综合救治新疗法 31例 ,死亡 10例 ,病死率为 32 .2 5 %。结论　MODS及多器官衰竭 (MOF)病因复杂 ,治疗困难 ,死亡率高 。Objective To explore some treating measures to decrease the mortality of the abdominal surgical diseases combined with MODS.?Methods (1)?Present synthesis treating measure is to use great dosage of anisodaminum and dexamethasone together for a short time.(2)?While treating MODS,inflammatory medium,bacterias,exotoxin,endotoxin,dysfunction of microcirculation,immunity,nutrition,choronic diseases and the function of organs should be paid more attention to and cured as well.(3)?Nourishment support treatment has been adopted.(4)?JIEDUGUBENTANG developed by ourselves was used cooperatively to improve immunity and adjust the deliverance of inflammatory medium.?Results Fifty nine patients died in 118 patients(the mortality 50.00%).Forty nine patients died in the 87 patients cured with traditional routine methods(the mortality 56.32%).Ten cases died and 21 cases were cured with the new synthesis treating measures(the mortality 32.25%).?Conclusion The pathogenes of MODS is complex and it is difficult to be cured.The mortality can be decreased by using new synthesis treating measures.

关 键 词：腹部外科疾病 并发症 多器官功能综合征 中西医结合治疗 

分 类 号：R656[医药卫生—外科学] R59[医药卫生—临床医学]