BSAP/Pax-5在B淋巴细胞发育、增殖、分化中的作用  

Effect of BSAP/Pax-5 on the Development, Proliferation and Differentiation of B Lymphocyte Cell

作　　者：谭余庆[1] 张永祥[1] 

机构地区：[1]军事医学科学院毒物药物研究所,北京100850

出　　处：《生理科学进展》2001年第2期125-128,共4页Progress in Physiological Sciences

摘　　要：BSAP ,一个B细胞特异性激活蛋白 ,由Pax 5转录的核蛋白。作为核转录因子 ,其在B细胞的发育、增殖和分化中起重要作用。同时也影响B细胞分化晚期的Ig的分泌。BSAP, a B cell lineage specific activator protein, is a nucleus transcription factor and is encoded by the Pax 5 gene. It is a critical modulator of B cell development, proliferation and differentiation. BSAP also influences B cell immunoglobulin secretion at later stages of B cell differentiation.

关 键 词：B细胞 信号转导 BSAP PAX-5 发育 细胞分化 增殖 

分 类 号：R392.12[医药卫生—免疫学] Q25[医药卫生—基础医学]