广东省1988-1998年流感流行与监测分析  

Analysis on Influenza Epidemic and Surveillance in Guangdong between 1988 and 1998

作　　者：黄平[1] 陈伟师[1] 倪汉忠[1] 周惠琼[1] 刘少梅[1] 

机构地区：[1]广东省疾病预防控制中心,广州510300

出　　处：《海峡预防医学杂志》2001年第2期15-17,共3页Strait Journal of Preventive Medicine

基　　金：美国疾病控制中心 (CDC)的 WHO流感项目基金资助!(976 8931);卫生部流感专项基金资助!(980 32 4)

摘　　要：[目的 ]了解广东地区流感流行情况 ,探讨流行特征 ,提供防治建议。 [方法 ]建立全省流感监测网 ,进行流行病学和病原学调查。 [结果 ]1988- 1998年流感流行高峰在每年的 3～ 7月 ,其中 7年流行优势毒株为 H3N2 毒株。由于发生明显的血清学抗原漂移 ,1996年 H3N2 毒株引起广东地区流感流行。 1998年禽流感监测中 ,从 9例患者流感鼻咽拭子中分离到 H9N2 流感毒株 ,与此同时 ,从鸡群分离到禽 H9N2 毒株。[结论 ]广东地区每年只有一个流感流行峰 ,目前 H3N2 流感毒株仍是广东地区的优势毒株 ,流感 H9N2 毒株对人类的致病性值得进一步探讨。Objective] To investigate the epidemiological characteristics of influenza and provide the control measures [Methods] To establish the influenza surveillance network and investigate the influenza epidemic and pathogen [Results] The epidemic peaks were annually on March to July in Guangdong in 1988-1998,The epidemic in 7 years was predominated by H 3N 2 strain The outbreak of influenza occurred in 1996 because of the remarkable antigenic drift of H 3N 2 strain The H 9N 2 strains were isolated from 9 patients and the chicken in 1998 [Conclusion] There is one epidemic peak annually in the province The epidenic is predominated by H 3N 2 strain in Guangdong province.It is worth to research the pathogenicity of influenza H 9N 2 in the future.

关 键 词：流感病毒 流行 抗原变异 监测 广东 

分 类 号：R511.701[医药卫生—内科学]