纳洛酮在海洛因急性中毒抢救中的临床应用  

CLINICAL USE OF NALOXONE IN THE TREATMENT OF ACUTE HEROIN POISONING

作　　者：谈绍强 曾水金 曾亮 马甲荣 胡国志 

机构地区：[1]广州市槎头戒毒治疗中心,广州510435 [2]广州市火村戒毒所,广州510530

出　　处：《中国药物依赖性杂志》2001年第2期109-110,145,共3页Chinese Journal of Drug Dependence

摘　　要：目的··:研究纳洛酮在海洛因急性中毒病例中的临床应用。方法··:对入院的急性中毒患者立即静脉注射(iv)阿片类受体拮抗剂纳洛酮 ,以迅速扭转海洛因对呼吸的抑制并进行综合治疗。结果··:94例患者呼吸改善 ,意识恢复 ,抢救成功率95.91 %。结论··:纳洛酮用于海洛因急性中毒的临床抢救 ,疗效理想 ,对意识恢复、呼吸抑制的改善作用明显 ,不良反应轻微 ,常规剂量无依赖性 ,可作为海洛因急性中毒时发生呼吸抑制的首选治疗药物 。Objective: To study the clinical use of naloxone in the treatment of acute heroin poisoning. Method: Patients diagnosed as acute heroin poisoning were administered (iv)naloxone right after they were in hospital to relieve their respiratory inhibition induced by heroin and started general treatment.Result:Of all patients,95.91%(94 cases)was saved to life,whose respiratory condition had improved and consciousness recovered. Conclusion: Naloxone is effective in rescuing acute heroin toxic patients,especially in the recovery of consciousness and improvement of respiratory condition of the patients.Its adverse reaction is slight and with routine dosage,it dose not produce drug dependence.

关 键 词：纳洛酮 海洛因急性中毒 呼吸抑制 治疗 

分 类 号：R595.505[医药卫生—内科学]