中药巴布剂制备工艺的实验研究  

Experimental Studies on the Techniques of Cataplasm Contained Chinese Herbal Medicines

作　　者：刘淑芝[1] 费虹[1] 汤亚池[1] 郭春燕[1] 张蔚君[2] 

机构地区：[1]中国中医研究院中药研究所,北京100700 [2]北京空军总医院,北京100036

出　　处：《中国实验方剂学杂志》2001年第3期9-11,共3页Chinese Journal of Experimental Traditional Medical Formulae

摘　　要：选用正交实验法 ,以膏体的均匀性、膜残留性、柔软性、可涂展性及对皮肤的追随性为综合考察指标 ,以剥离时粘着力 (180°)为量化指标 ,对影响巴布剂膏体物理性状的因素 :搅拌时间、炼合温度、各组分基质的添加顺序三个因素进行实验研究 ,并对最佳条件进行优选。结果表明 :制备工艺的最佳条件为 :搅拌 2 0～ 40min ;膏体温度 5 0℃ ;赋形剂组分先与填充剂组合混合后 ,再加入粘性剂。The factors effecting the physical property of cataplasm were investigated by means of the homogeneity,layer residue,flexibility and adhesive ability of the plaster as comprehensive consideration,and adhesive force(180°) while exfoliated as the quantitative marker.The main factors,stirring time,refining temperature,and adding order of matrixs were studied by orthogonal design tests.The optimized procedures were stirring for 20～40minute,plaster at 50℃,and after mixing the excipients and filling material,then adding the bonds.

关 键 词：制备工艺 基质 正交设计 中药 巴布剂 

分 类 号：R283.6[医药卫生—中药学]